Bhardwaj Anubhuti, Narain Upma, Gupta Arvind
Department of Medicine, MLN Medical College, Prayagraj, India.
Tejas Microdiagnostics, Prayagraj, India.
Indian Heart J. 2022 May-Jun;74(3):249-250. doi: 10.1016/j.ihj.2022.03.004. Epub 2022 Mar 21.
Our study aims to evaluate the role of neutrophil gelatinase associated lipocalin (NGAL) as an early surrogate marker in predicting acute kidney injury (AKI) and mortality in cardiac ICU patients. The study was conducted at SRN Hospital, excluding those with known renal diseases. Out of 152 patients, 56 developed AKI (cases) and 96 were our controls. Higher NGAL was associated with increased mortality rates (P = 0.0201 and 0.0255 for serum and urinary NGAL respectively). Our study concluded that NGAL measurement at admission may be a boon in improving the outcome of cardiac ICU patients.
我们的研究旨在评估中性粒细胞明胶酶相关脂质运载蛋白（NGAL）作为预测心脏重症监护病房（ICU）患者急性肾损伤（AKI）和死亡率的早期替代标志物的作用。该研究在SRN医院进行，排除了已知患有肾脏疾病的患者。152例患者中，56例发生了AKI（病例组），96例为对照组。较高的NGAL与死亡率增加相关（血清和尿NGAL的P值分别为0.0201和0.0255）。我们的研究得出结论，入院时测量NGAL可能有助于改善心脏ICU患者的预后。
