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免疫功能低下患者的导管相关菌血症。

catheter-related bacteraemia in an immunocompromised patient.

机构信息

University of Kansas School of Medicine, Kansas City, Kansas, USA

Internal Medicine, The University of Kansas Health System, Kansas City, Kansas, USA.

出版信息

BMJ Case Rep. 2022 Mar 24;15(3):e247496. doi: 10.1136/bcr-2021-247496.

DOI:10.1136/bcr-2021-247496
PMID:35332006
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8948387/
Abstract

A 34-year-old man on active chemotherapy was hospitalised with fever, chills and rigours after power-washing a pig pen on a farm. His blood cultures grew , a gram-negative rod in the family, which has been isolated from a variety of environments including soil, surface water, as well as in the gastrointestinal flora of farm animals. The likely source of infection was his tunnelled central venous catheter exposed to water contaminated by faeces when he was washing the pig pen. While there have been several cases reported of catheter-related bacteraemia, to our knowledge there are very few reports of infection spread in this manner.

摘要

一位 34 岁正在接受积极化疗的男性,因在农场清洗猪圈后出现发热、寒战和肌肉痉挛而住院。他的血液培养物中生长出一种革兰氏阴性杆菌,这种杆菌存在于多种环境中,包括土壤、地表水以及农场动物的胃肠道菌群中。感染的可能来源是他的隧道式中心静脉导管,在清洗猪圈时暴露于被粪便污染的水中。虽然已经有几例导管相关菌血症的报道,但据我们所知,这种方式传播感染的报道非常少。

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本文引用的文献

1
Catheter-Related ESBL-Producing Septicemia in Hemodialysis Patient: An Emerging Pathogen?血液透析患者中与导管相关的产超广谱β-内酰胺酶败血症:一种新出现的病原体?
Case Rep Infect Dis. 2020 Jan 21;2020:7403152. doi: 10.1155/2020/7403152. eCollection 2020.
2
Peritonitis from : An emerging pathogen.源自:一种新兴病原体的腹膜炎。
Clin Case Rep. 2019 Mar 18;7(4):829-831. doi: 10.1002/ccr3.2094. eCollection 2019 Apr.
3
Leclercia adecarboxylata: a case report and literature review of 74 cases demonstrating its pathogenicity in immunocompromised patients.产酸克雷伯菌:74 例病例的报告及文献复习,表明其在免疫功能低下患者中有致病性。
Infect Dis (Lond). 2019 Mar;51(3):179-188. doi: 10.1080/23744235.2018.1536830. Epub 2018 Nov 29.
4
Presence of Stenotrophomonas maltophilia exhibiting high genetic similarity to clinical isolates in final effluents of pig farm wastewater treatment plants.在养猪场废水处理厂的最终废水中存在与临床分离株具有高度遗传相似性的嗜麦芽寡养单胞菌。
Int J Hyg Environ Health. 2018 Mar;221(2):300-307. doi: 10.1016/j.ijheh.2017.12.002. Epub 2017 Dec 8.
5
Genomic characterisation of clinical and environmental Pseudomonas putida group strains and determination of their role in the transfer of antimicrobial resistance genes to Pseudomonas aeruginosa.临床和环境假单胞菌群体菌株的基因组特征及其在将抗菌药物耐药基因转移到铜绿假单胞菌中的作用的确定。
BMC Genomics. 2017 Nov 10;18(1):859. doi: 10.1186/s12864-017-4216-2.
6
Is Leclercia adecarboxylata a new and unfamiliar marine pathogen?无羧基勒克氏菌是一种新的、不常见的海洋病原体吗?
J Clin Microbiol. 2014 May;52(5):1775-6. doi: 10.1128/JCM.03239-13. Epub 2014 Feb 12.
7
Leclercia adecarboxylata and catheter-related bacteraemia: review of the literature and outcome with regard to catheters and patients.产脱羧勒克菌与导管相关血流感染:文献回顾及导管和患者预后。
J Med Microbiol. 2013 Oct;62(Pt 10):1620-1623. doi: 10.1099/jmm.0.059535-0. Epub 2013 Jul 23.
8
Catheter-related bacteremia caused by multidrug-resistant Leclercia adecarboxylata in a patient with breast cancer.导管相关的耐药性阿克曼氏菌引起的菌血症 1 例乳腺癌患者
J Clin Microbiol. 2012 Sep;50(9):3129-32. doi: 10.1128/JCM.00948-12. Epub 2012 Jul 3.
9
Leclercia adecarboxylata bacteremia in a trauma patient: case report and review of the literature.创伤患者中去羧基勒克菌血流感染:病例报告及文献复习。
Surg Infect (Larchmt). 2012 Feb;13(1):63-6. doi: 10.1089/sur.2010.093. Epub 2012 Jan 4.
10
Leclercia adecarboxylata, an unusual hemodialysis catheter-related infection.脱羧勒克菌,一种罕见的与血液透析导管相关的感染。
Int Urol Nephrol. 2011 Dec;43(4):1257-8. doi: 10.1007/s11255-011-0002-2. Epub 2011 May 29.