Center of Research on Psychological and Somatic disorders, Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands.
Department of Health Sciences, The EMGO+ Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands.
J Clin Nurs. 2023 Apr;32(7-8):1370-1380. doi: 10.1111/jocn.16299. Epub 2022 Mar 24.
The self-performance of a Five-Times-Sit-To-Stand (FTSTS)-test, without the usual supervision by a medical professional, provides valuable opportunities for clinical practice and research. This study aimed: (1) to determine the validity of the self-performed FTSTS test in comparison to a supervised reference test and (2) to determine the reliability of a self-performed FTSTS test by cancer survivors.
Early detection of frailty in cancer survivors may enable prehabilitation interventions before surgery or intensive treatment, improving cancer outcomes.
A repeated measures reliability and agreement study, with one week in between measures, was performed.
Cancer survivors (n = 151) performed two FTSTS tests themselves. One additional reference FTSTS test was supervised by a physical therapist. The intraclass correlation coefficient (ICC), structural error of measurement (SEM) and minimally important clinical difference (MID) were calculated comparing a self-performed FTSTS test to the reference test, and comparing two self-performed FTSTS tests. The Guidelines for Reporting Reliability and Agreement Studies (GRASS) have been used.
Mean age of cancer survivors was 65.6 years (SD = 9.3), 54.6% were female, median time since diagnosis was 2 years [IQR = 1], and tumour type varied (e.g., breast cancer (31.8%), prostate cancer (17.2%), gastrointestinal cancer (11.9%) and haematological cancer (11.9%)). Validity of the self-performed FTSTS test at home was acceptable in comparison with the reference test (ICC = .74; SEM = 3.2; MID = 3.6) as was the reliability of the self-performed FTSTS test (ICC = .70; SEM = 2.2; MID = 3.8).
The self-performed FTSTS test is a valid and reliable measure to assess lower body function and has potential to be used as objective (pre-)screening tool for frailty in cancer survivors.
The self-performed FTSTS test at home may indicate the cancer survivors in need of prehabilitation in advance of surgery or intensive treatment. The feasibility, short amount of time needed and potential cost-effectiveness of the self-performed FTSTS test can make it a valuable contribution to personalised care and precision medicine.
五次坐站测试（FTSTS）无需医疗专业人员的常规监督即可自行完成，这为临床实践和研究提供了有价值的机会。本研究旨在：（1）确定自我执行的 FTSTS 测试与监督参考测试的有效性；（2）通过癌症幸存者确定自我执行的 FTSTS 测试的可靠性。
早期发现癌症幸存者的虚弱状态可以在手术或强化治疗之前进行预康复干预，从而改善癌症结局。
进行了一项重复测量可靠性和一致性研究，两次测量之间间隔一周。
癌症幸存者（n=151）自行进行了两次 FTSTS 测试。一次额外的参考 FTSTS 测试由物理治疗师监督。使用组内相关系数（ICC）、测量结构性误差（SEM）和最小临床差异（MID）来比较自我执行的 FTSTS 测试与参考测试，并比较两次自我执行的 FTSTS 测试。已使用可靠性和一致性研究指南（GRASS）。
癌症幸存者的平均年龄为 65.6 岁（标准差=9.3），54.6%为女性，中位诊断后时间为 2 年[IQR=1]，肿瘤类型多样（例如，乳腺癌（31.8%）、前列腺癌（17.2%）、胃肠道癌（11.9%）和血液癌（11.9%））。与参考测试相比，在家中自行进行的 FTSTS 测试的有效性是可以接受的（ICC=.74；SEM=3.2；MID=3.6），自我执行的 FTSTS 测试的可靠性也是可以接受的（ICC=.70；SEM=2.2；MID=3.8）。
自我执行的 FTSTS 测试是一种评估下半身功能的有效且可靠的方法，具有作为癌症幸存者虚弱的客观（预）筛查工具的潜力。
在家中自行进行的 FTSTS 测试可能可以提前确定需要进行术前或强化治疗的癌症幸存者。自我执行的 FTSTS 测试具有可行性、所需时间短且潜在的成本效益，因此可以为个性化护理和精准医学做出有价值的贡献。
