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酒精性肝疾病患者铜和锌缺乏:一个治疗困境的病例报告。

Copper and zinc deficiency in an alcoholic patient: a case report of a therapeutic dilemma.

机构信息

Division of Hospital Medicine, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.

出版信息

J Addict Dis. 2022 Oct-Dec;40(4):583-587. doi: 10.1080/10550887.2022.2030639. Epub 2022 Mar 25.

DOI:10.1080/10550887.2022.2030639
PMID:35332856
Abstract

Copper deficiency often manifests with anemia and ataxia. The risk factors associated with the deficiency include gastrointestinal surgery, excessive zinc supplementation, and malabsorptive conditions. Little is known about the relationship between copper deficiency and alcohol consumption. Here we report a case of copper deficiency in a patient with alcohol use disorder who also had zinc deficiency, thereby posing a therapeutic dilemma because copper and zinc are competitively absorbed into the small intestine. Early recognition of copper deficiency is essential when treating zinc deficiency in such patients.

摘要

铜缺乏症常表现为贫血和共济失调。与铜缺乏相关的危险因素包括胃肠道手术、过量补锌和吸收不良。关于铜缺乏与饮酒之间的关系,人们知之甚少。在此,我们报告一例酒精使用障碍患者铜缺乏的病例,该患者同时还缺锌,这给治疗带来了困境,因为铜和锌在小肠中会竞争性吸收。在治疗此类患者的锌缺乏症时,早期识别铜缺乏症至关重要。

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