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微生物种类多样且功能各异的群落生产聚羟基脂肪酸酯(PHA)的趋势

Trends in PHA Production by Microbially Diverse and Functionally Distinct Communities.

作者信息

Angra Vani, Sehgal Rutika, Gupta Reena

机构信息

Department of Biotechnology, Himachal Pradesh University, Summerhill, Shimla, 171005, India.

出版信息

Microb Ecol. 2023 Feb;85(2):572-585. doi: 10.1007/s00248-022-01995-w. Epub 2022 Mar 25.

Abstract

Along with the wide applications of conventional plastics, they have a large number of disadvantages like their non-biodegradable nature, dependency on fossil fuels and the release of large amounts of toxic materials in the environment. Therefore, to resolve these problems, a number of bioplastics are studied, out of which polyhydroxyalkanoates are considered as the best alternatives. Polyhydroxyalkanoates (PHAs) are produced by microorganisms as intracellular granules during stressful conditions. Though a wide range of organisms can naturally produce PHAs, only a few of them can be used for commercial production. Therefore, more diverse organisms that accumulate a considerable amount of PHAs and also reduce the production cost need to be exploited. Transgenic plants, recombinant bacteria, algae and extremophiles are some diverse organisms that produce a high amount of PHAs at a low cost. So, if potential organisms are used for PHA production, bioplastics will be able to completely replace petroleum-based polymers. Therefore, our review mainly focuses on production of PHAs using potential organisms so that amount of PHAs produced is high and cost-effective which would further help in the commercialization of PHAs.

摘要

随着传统塑料的广泛应用,它们存在大量缺点,如不可生物降解、依赖化石燃料以及在环境中释放大量有毒物质。因此,为了解决这些问题,人们研究了多种生物塑料,其中聚羟基脂肪酸酯被认为是最佳替代品。聚羟基脂肪酸酯(PHA)是微生物在应激条件下作为细胞内颗粒产生的。虽然有多种生物能够自然产生PHA,但只有少数几种可用于商业生产。因此,需要开发更多能积累大量PHA且能降低生产成本的不同生物。转基因植物、重组细菌、藻类和极端微生物是一些能低成本大量生产PHA的不同生物。所以,如果将潜在生物用于PHA生产,生物塑料将能够完全替代石油基聚合物。因此,我们的综述主要关注利用潜在生物生产PHA,以使PHA的产量高且具有成本效益,这将进一步有助于PHA的商业化。

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