Beijing National Laboratory of Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, Beijing 100190, China; School of Chemical Sciences, University of Chinese Academy of Sciences, 19A Yuquanlu, Beijing 100049, China.
Beijing National Laboratory of Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, Beijing 100190, China; School of Chemical Sciences, University of Chinese Academy of Sciences, 19A Yuquanlu, Beijing 100049, China.
J Chromatogr A. 2022 May 10;1670:462957. doi: 10.1016/j.chroma.2022.462957. Epub 2022 Mar 10.
Open-tubular capillary electrochromatography (OT-CEC) is an important tool in separation science due to its effective performance and reusability, and has attracted attention because the coating-process and the coating thickness can be controlled. Although dozens of OT-CEC reviews have been published recently, design of the smart polymer coatings, which can improve the separation efficiency of OT-CEC via external stimuli, remains a challenge. This review describes the advancement of research on OT-CEC stimuli-responsive polymeric coatings (SR-PCs). It covers the latest researches in the design and synthesis of stimuli-responsive polymers, the protocols for their fabrication on capillary inner surfaces, strategies for improving stimuli-responsive OT-CEC separation efficiency and real-world applications.
开管毛细管电色谱（OT-CEC）因其高效性能和可重复使用性而成为分离科学中的重要工具，并且由于其涂层工艺和涂层厚度可控制而受到关注。尽管最近已经发表了数十篇 OT-CEC 评论，但设计能够通过外部刺激改善 OT-CEC 分离效率的智能聚合物涂层仍然是一个挑战。本综述描述了用于 OT-CEC 刺激响应聚合物涂层（SR-PCs）的研究进展。它涵盖了刺激响应聚合物的设计和合成方面的最新研究，在毛细管内表面上制造它们的方案，以及改善刺激响应 OT-CEC 分离效率和实际应用的策略。
