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阿奇霉素遭抢购：意大利从新冠疫情中吸取的抗生素滥用教训。

Azithromycin Has Been Flying Off the Shelves: The Italian Lesson Learnt from Improper Use of Antibiotics against COVID-19.

机构信息

Center for Public Health Research, School of Medicine and Surgery, University of Milan-Bicocca, 20900 Monza, Italy.

Department of Experimental Medicine, School of Medicine and Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

出版信息

Medicina (Kaunas). 2022 Mar 1;58(3):363. doi: 10.3390/medicina58030363.

DOI:10.3390/medicina58030363
PMID:35334539
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8955327/
Abstract

The warning by the Italian Medicines Agency on the high shortage of azithromycin in the country in January 2022 represents a paradigmatic lesson learnt from improper use of antibiotics during COVID-19 pandemic.

摘要

2022 年 1 月，意大利药品管理局发出警告称该国阿奇霉素严重短缺，这是在 COVID-19 大流行期间不当使用抗生素所吸取的一个典型教训。

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本文引用的文献

1
Impact of azithromycin mass drug administration on the antibiotic-resistant gut microbiome in children: a randomized, controlled trial.阿奇霉素群体给药对儿童抗生素耐药性肠道微生物群的影响：一项随机对照试验。
Gut Pathog. 2022 Jan 6;14(1):5. doi: 10.1186/s13099-021-00478-6.
2
Impact of SARS-CoV-2 Epidemic on Antimicrobial Resistance: A Literature Review.SARS-CoV-2 疫情对抗菌药物耐药性的影响：文献综述。
Viruses. 2021 Oct 20;13(11):2110. doi: 10.3390/v13112110.
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How conspiracists exploited COVID-19 science.阴谋论者如何利用新冠病毒科学。
Nat Hum Behav. 2021 Nov;5(11):1464-1465. doi: 10.1038/s41562-021-01217-2.
4
COVID-19 Scientific Facts vs. Conspiracy Theories: Is Science Failing to Pass Its Message?新冠病毒科学事实与阴谋论：科学是否未能传递其信息？
Int J Environ Res Public Health. 2021 Jun 11;18(12):6343. doi: 10.3390/ijerph18126343.
5
Analysis of the time evolution of COVID-19 lethality during the first epidemic wave in Italy.分析意大利首次疫情期间 COVID-19 致死率的时间演变。
Acta Biomed. 2021 May 12;92(2):e2021171. doi: 10.23750/abm.v92i2.11149.
6
[The use of antibiotics in Italy. The national OsMed report 2019.].[意大利抗生素的使用情况。2019年国家OsMed报告。]
Recenti Prog Med. 2021 Mar;112(3):186-190. doi: 10.1701/3565.35456.
7
Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.阿奇霉素用于英国有不良临床病程风险增加人群的疑似 COVID-19 社区治疗（PRINCIPLE）：一项随机、对照、开放标签、适应性平台试验。
Lancet. 2021 Mar 20;397(10279):1063-1074. doi: 10.1016/S0140-6736(21)00461-X. Epub 2021 Mar 4.
8
Macrolide and Nonmacrolide Resistance with Mass Azithromycin Distribution.大剂量阿奇霉素分发与大环内酯类和非大环内酯类耐药性。
N Engl J Med. 2020 Nov 12;383(20):1941-1950. doi: 10.1056/NEJMoa2002606.
9
Italian young doctors' knowledge, attitudes and practices on antibiotic use and resistance: A national cross-sectional survey.意大利青年医生对抗生素使用和耐药性的知识、态度和实践：一项全国性横断面调查。
J Glob Antimicrob Resist. 2020 Dec;23:167-173. doi: 10.1016/j.jgar.2020.08.022. Epub 2020 Sep 21.