Clinic of Infectious Diseases, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Clinic of Infectious Diseases, University of Bari, 70121 Bari, Italy.
Viruses. 2021 Oct 20;13(11):2110. doi: 10.3390/v13112110.
Antimicrobial resistance is an urgent threat to public health and global development; in this scenario, the SARS-CoV2 pandemic has caused a major disruption of healthcare systems and practices. A narrative review was conducted on articles focusing on the impact of COVID-19 on multidrug-resistant gram-negative, gram-positive bacteria, and fungi. We found that, worldwide, multiple studies reported an unexpected high incidence of infections due to methicillin-resistant , carbapenem-resistant , carbapenem-resistant Enterobacteriaceae, and among COVID-19 patients admitted to the intensive care unit. In this setting, inappropriate antimicrobial exposure, environmental contamination, and discontinuation of infection control measures may have driven selection and diffusion of drug-resistant pathogens.
抗微生物药物耐药性是对公共卫生和全球发展的紧迫威胁；在这种情况下，SARS-CoV2 大流行严重扰乱了医疗保健系统和实践。对重点关注 COVID-19 对多药耐药革兰氏阴性、革兰氏阳性细菌和真菌影响的文章进行了叙述性综述。我们发现，在全球范围内，多项研究报告称，重症监护病房收治的 COVID-19 患者中，耐甲氧西林、耐碳青霉烯、耐碳青霉烯肠杆菌科和 的感染发生率出乎意料地高。在这种情况下，不适当的抗菌药物暴露、环境污染和感染控制措施的中断可能推动了耐药病原体的选择和传播。
