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未训练的非虚弱 80 岁高龄受试者的最大运动心肺功能参数。

Sub Maximal Ergospirometry Parameters in Untrained Non-Frail Octogenarian Subjects.

机构信息

Laboratory of Sciences of Physical Activity, Sport and Health, Faculty of Medical Sciences, Universidad de Santiago de Chile, Santiago 9170022, Chile.

Human Performance Lab, Education, Physical Activity and Health Research Unit (GEEAFyS), Universidad Católica del Maule, Talca 3460000, Chile.

出版信息

Medicina (Kaunas). 2022 Mar 3;58(3):378. doi: 10.3390/medicina58030378.

DOI:10.3390/medicina58030378
PMID:35334553
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8952334/
Abstract

: The prevalence of chronic diseases increases with age, and in octogenarian elderly, a cardiorespiratory test with gas analysis is more effective in determining the risk of mortality than applying the conventional risk factors. : 25 untrained non-frail octogenarian subjects (four men) performed a submaximal test with gas analysis, which was stopped after the second ventilatory threshold (VT2) was reached. The variables analyzed were oxygen consumption at the first threshold (VO VT1); ventilatory class (VE/VCO); oxygen uptake efficiency slope (OUES); cardiorespiratory optimal point (COP); oxygen pulse difference between VT2 and VT1 (diff. VO/HR VT2-VT1). : the variables were classified categorically based on cut-off points present in the literature, where the variable with the highest percentage of altered cases was dif. VO2/HR VT2-VT1 at 48%; followed by VO VT1 at 40%, OUES at 36%, COP at 32%, and VE/VCO at 24%. Chi-square analysis between the measured parameters defined that normal and altered variables were related to each other, except for the variable VE/VCO and OUES. : it was found that the main altered variable was the oxygen pulse and the least altered variable was VCO/VCO; there was only a statistically significant difference in a pair of OUES vs. VE/VCO variables.

摘要

随着年龄的增长,慢性病的患病率增加,在 80 岁以上的老年人中,与应用传统危险因素相比,进行带气体分析的心肺测试更能有效确定死亡风险。 25 名未经训练的非虚弱 80 岁以上老年人(4 名男性)进行了带气体分析的亚最大强度测试,当达到第二个通气阈值 (VT2) 后停止测试。分析的变量包括第一阈值时的耗氧量 (VO VT1);通气分级 (VE/VCO);摄氧量效率斜率 (OUES);心肺最佳点 (COP);VT2 与 VT1 之间的氧脉冲差 (diff. VO/HR VT2-VT1)。 根据文献中存在的截止点对变量进行分类,其中改变病例百分比最高的变量是 diff. VO2/HR VT2-VT1 为 48%;其次是 VO VT1 为 40%,OUES 为 36%,COP 为 32%,VE/VCO 为 24%。测量参数之间的卡方分析表明,正常和改变的变量相互关联,除了 VE/VCO 和 OUES 变量。 结果发现,主要改变的变量是氧脉冲,改变最小的变量是 VCO/VCO;仅在 OUES 与 VE/VCO 变量对之间存在统计学差异。

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本文引用的文献

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The prognostic value of the cardiorespiratory optimal point during submaximal exercise testing in heart failure.次极量运动试验中心肺最佳点在心力衰竭中的预后价值。
Rev Port Cardiol. 2022 Sep;41(9):751-758. doi: 10.1016/j.repc.2021.06.023. Epub 2022 Jul 12.
2
Cardiorespiratory fitness assessment using risk-stratified exercise testing and dose-response relationships with disease outcomes.使用风险分层运动测试和疾病结局的剂量反应关系评估心肺适能。
Sci Rep. 2021 Jul 28;11(1):15315. doi: 10.1038/s41598-021-94768-3.
3
Prognostic Relevance of Cardiorespiratory Fitness as Assessed by Submaximal Exercise Testing for All-Cause Mortality: A UK Biobank Prospective Study.
亚极量运动试验评估的心肺适能对全因死亡率的预后相关性:英国生物银行前瞻性研究。
Mayo Clin Proc. 2020 May;95(5):867-878. doi: 10.1016/j.mayocp.2019.12.030.
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Inside OUES: fact or fiction?在OUES内部:事实还是虚构?
Eur J Prev Cardiol. 2019 Jan;26(2):174-176. doi: 10.1177/2047487318814977. Epub 2018 Nov 22.
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Relative peak exercise oxygen pulse is related to sudden cardiac death, cardiovascular and all-cause mortality in middle-aged men.相对峰值运动氧脉搏与中年男性的心脏性猝死、心血管疾病和全因死亡率相关。
Eur J Prev Cardiol. 2018 May;25(7):772-782. doi: 10.1177/2047487318761679. Epub 2018 Feb 28.
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Clinical, scintigraphic, and angiographic predictors of oxygen pulse abnormality in patients undergoing cardiopulmonary exercise testing.心肺运动试验患者氧脉搏异常的临床、闪烁扫描和血管造影预测因素。
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Cardiorespiratory optimal point during exercise testing as a predictor of all-cause mortality.运动测试期间的心肺最佳点作为全因死亡率的预测指标。
Rev Port Cardiol. 2017 Apr;36(4):261-269. doi: 10.1016/j.repc.2016.09.017. Epub 2017 Mar 17.
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