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生物相容性钛合金的力学特性及体外分析

Mechanical Characterization and In Vitro Assay of Biocompatible Titanium Alloys.

作者信息

Baltatu Iustinian, Sandu Andrei Victor, Vlad Maria Daniela, Spataru Mihaela Claudia, Vizureanu Petrica, Baltatu Madalina Simona

机构信息

Faculty of Materials Science and Engineering, "Gheorghe Asachi" Technical University of Iasi, 41 "D. Mangeron" Street, 700050 Iasi, Romania.

Romanian Inventors Forum, Str. Sf. P. Movila 3, 700089 Iasi, Romania.

出版信息

Micromachines (Basel). 2022 Mar 10;13(3):430. doi: 10.3390/mi13030430.

DOI:10.3390/mi13030430
PMID:35334722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8953245/
Abstract

Metals that come into contact with the body can cause reactions in the body, so biomaterials must be tested to avoid side effects. Mo, Zr, and Ta are non-toxic elements; alloyed with titanium, they have very good biocompatibility properties and mechanical properties. The paper aims to study an original Ti20Mo7ZrTa system (5, 10, 15 wt %) from a mechanical and in vitro biocompatibility point of view. Alloys were examined by optical microstructure, tensile strength, fractographic analysis, and in vitro assay. The obtained results indicate very good mechanical and biological properties, recommending them for future orthopedic medical applications.

摘要

与身体接触的金属会在体内引发反应,因此生物材料必须经过测试以避免副作用。钼、锆和钽是无毒元素;与钛合金化后,它们具有非常好的生物相容性和机械性能。本文旨在从力学和体外生物相容性的角度研究一种原始的Ti20Mo7ZrTa体系(5%、10%、15%重量百分比)。通过光学微观结构、拉伸强度、断口分析和体外试验对合金进行了检测。所得结果表明其具有非常好的力学和生物学性能,推荐将其用于未来的骨科医学应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/1b23bfc6201d/micromachines-13-00430-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/ffe917c644ce/micromachines-13-00430-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/5c2b7e500e54/micromachines-13-00430-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/354ec1e5d0d0/micromachines-13-00430-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/1f4d8543a69e/micromachines-13-00430-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/fb3ee3bff9a8/micromachines-13-00430-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/1b23bfc6201d/micromachines-13-00430-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/ffe917c644ce/micromachines-13-00430-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/5c2b7e500e54/micromachines-13-00430-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/354ec1e5d0d0/micromachines-13-00430-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/1f4d8543a69e/micromachines-13-00430-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/fb3ee3bff9a8/micromachines-13-00430-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8321/8953245/1b23bfc6201d/micromachines-13-00430-g006.jpg

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10
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Mater Sci Eng C Mater Biol Appl. 2014 Jan 1;34:354-9. doi: 10.1016/j.msec.2013.09.032. Epub 2013 Sep 28.