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用于潜在植入应用的钛-钼-锆-钽-硅合金的设计、合成与初步评估

Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications.

作者信息

Baltatu Madalina Simona, Spataru Mihaela Claudia, Verestiuc Liliana, Balan Vera, Solcan Carmen, Sandu Andrei Victor, Geanta Victor, Voiculescu Ionelia, Vizureanu Petrica

机构信息

Department of Technologies and Equipments for Materials Processing, Faculty of Materials Science and Engineering, Gheorghe Asachi Technical University of Iaşi, Blvd. Mangeron, No. 51, 700050 Iasi, Romania.

Public Health Department, Faculty of Veterinary Medicine, "Ion Ionescu de la Brad" University of Life Sciences, 3 Mihail Sadoveanu Alley, 700490 Iasi, Romania.

出版信息

Materials (Basel). 2021 Nov 11;14(22):6806. doi: 10.3390/ma14226806.

Abstract

Considering the future trends of biomaterials, current studies are focused on the corrosion resistance and the mechanical properties of new materials that need to be considered in the process of strengthening alloys with additive non-toxic elements. Many kinds of titanium alloys with different biocompatible elements (Mo, Si, Zr, etc.,) have been recently developed for their similar properties with human bone. Four new different alloys were obtained and investigated regarding their microstructure, mechanical, chemical, and biological behavior (in vitro and in vivo evaluation), the alloys are as follows: Ti15Mo7Zr15Ta, Ti15Mo7Zr15Ta0.5Si, Ti15Mo7Zr15Ta0.75Si, and Ti15Mo7Zr15Ta1Si. There were changes with the addition of the silicon element such as the hardness and the modulus of elasticity increased. An MTT assay confirmed the in vitro cytocompatibility of the prepared alloys.

摘要

考虑到生物材料的未来发展趋势,当前的研究集中在新型材料的耐腐蚀性和机械性能上,在使用无毒添加元素强化合金的过程中需要考虑这些性能。最近开发了多种含有不同生物相容性元素(钼、硅、锆等)的钛合金,因为它们与人体骨骼具有相似的特性。获得了四种新型不同合金,并对其微观结构、机械、化学和生物学行为(体外和体内评估)进行了研究,这些合金如下:Ti15Mo7Zr15Ta、Ti15Mo7Zr15Ta0.5Si、Ti15Mo7Zr15Ta0.75Si和Ti15Mo7Zr15Ta1Si。随着硅元素的添加出现了一些变化,如硬度和弹性模量增加。MTT分析证实了所制备合金的体外细胞相容性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bab/8621571/c98b9cc8dffc/materials-14-06806-g001.jpg

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