Moldovan Horațiu, Antoniac Iulian, Gheorghiță Daniela, Safta Maria Sabina, Preda Silvia, Broască Marian, Badilă Elisabeta, Fronea Oana, Scafa-Udrişte Alexandru, Cacoveanu Mihai, Molnar Adrian, Costache Victor Sebastian, Zaharia Ondin
Department of Cardiovascular Surgery, Bucharest Clinical Emergency Hospital, 014461 Bucharest, Romania.
Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Polymers (Basel). 2022 Mar 16;14(6):1189. doi: 10.3390/polym14061189.
Intraoperative haemostasis is of paramount importance in the practice of cardiovascular surgery. Over the past 70 years, topical haemostatic methods have advanced significantly and today we deal with various haemostatic agents with different properties and different mechanisms of action. The particularity of coagulation mechanisms after extracorporeal circulation, has encouraged the introduction of new types of topic agents to achieve haemostasis, where conventional methods prove their limits. These products have an important role in cardiac, as well as in vascular, surgery, mainly in major vascular procedures, like aortic dissections and aortic aneurysms. This article presents those agents used for topical application and the mechanism of haemostasis and offers general recommendations for their use in the operating room.
术中止血在心血管外科手术实践中至关重要。在过去的70年里，局部止血方法取得了显著进展，如今我们使用各种具有不同特性和作用机制的止血剂。体外循环后凝血机制的特殊性，促使人们引入新型局部用药来实现止血，而传统方法在此显示出了局限性。这些产品在心脏手术和血管手术中都发挥着重要作用，主要用于诸如主动脉夹层和主动脉瘤等大型血管手术。本文介绍了用于局部应用的这些药剂及其止血机制，并为其在手术室中的使用提供了一般性建议。
