Department of Surgical Sciences and Integrated Diagnostics, Laser Therapy Centre, University of Genoa, Viale Benedetto XV, 6, 16132 Genoa, Italy.
Department of Oral Surgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Sensors (Basel). 2022 Mar 15;22(6):2263. doi: 10.3390/s22062263.
This case report is aimed to demonstrate the synergetic effects of λ940 nm laser photobiomodulation (PBM) therapy in augmenting the advantages of high-level-laser treatment (HLLT)-mediated reaction orthodontic periodontal interface management. Materials and Methods: A 32-year-old female who presented with a persistent gummy smile of upper incisors and low upper midline frenum attachment post-orthodontic treatment, was seeking a better smile appearance. She had a history of delayed wound healing without underlying medical conditions; otherwise, she was fit and healthy. She underwent laser ablation of the upper midline frenum and gingivoplasty of the upper incisors region with λ940 nm and λ2780, respectively, as well as transcutaneous PBM therapy (λ940 nm) to accelerate wound healing. The laser protocols were as follows: λ2780 nm: power output-2 W, pulse width-60 μs, free running pulse (FRP), spot area-0.0016 cm, pulse repetition rate-25 pulses per second (s), 80 mJ/pulse, 90 s, λ940 nm: 1.2 W, continuous wave (CW) emission mode, 300 μm, 60 s; whereas the adjunctive λ940 nm induced-PBM parameters were as follows: power output-1.4 W, CW-120 s, single application, spot area-2.8 cm. An acceleration of the wound healing was observed on the 4th day of treatment with no immediate or post-operative complications. The results showed no functional or aesthetic relapses at a long-term follow-up of 6 months. The authors concluded that λ940 nm laser-PBM can provide a synergetic effect to HLLT in accelerating wound healing and offering a precision smile with minimal to none post-operative complications. It is safe and justifiable to utilise dual therapy over the conventional methods, which serves our patients' needs in our daily practice and in various clinical indications. The concept and laser protocols of this clinical case report can pave the roadmap for future extensive studies.
本病例报告旨在展示 λ940nm 激光光生物调节（PBM）疗法在增强高水平激光治疗（HLLT）介导的正畸牙周界面管理的优势方面的协同作用。
一名 32 岁女性，正畸治疗后出现上切牙持续性牙龈微笑和上中线系带附着低，寻求更好的微笑外观。她有延迟愈合的病史，但无潜在的医疗条件；除此之外，她身体健康。她接受了 λ940nm 和 λ2780nm 的激光消融上中线系带和龈成形术，以及经皮 PBM 治疗（λ940nm）以加速伤口愈合。激光方案如下：λ2780nm：功率输出-2W，脉冲宽度-60μs，自由运行脉冲（FRP），光斑面积-0.0016cm，脉冲重复率-25 脉冲/秒（s），80mJ/脉冲，90s，λ940nm：1.2W，连续波（CW）发射模式，300μm，60s；而辅助 λ940nm 诱导的 PBM 参数如下：功率输出-1.4W，CW-120s，单次应用，光斑面积-2.8cm。治疗第 4 天观察到伤口愈合加速，无即刻或术后并发症。6 个月的长期随访结果显示无功能或美学复发。作者得出结论，λ940nm 激光-PBM 可以与 HLLT 产生协同作用，加速伤口愈合，提供微创、术后并发症少的精准微笑。与传统方法相比，双重治疗是安全且合理的，能够满足我们患者在日常实践和各种临床适应症中的需求。本临床病例报告的概念和激光方案可以为未来的广泛研究铺平道路。
