Lwande Olivia Wesula, Thalin Therese, de Jong Johnny, Sjödin Andreas, Näslund Jonas, Evander Magnus, Ecke Frauke
Department of Clinical Microbiology, Umeå University, 901 85 Umea, Sweden.
Department of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, 901 83 Umea, Sweden.
Viruses. 2022 Mar 8;14(3):556. doi: 10.3390/v14030556.
The ongoing COVID-19 pandemic has stimulated a search for reservoirs and species potentially involved in back and forth transmission. Studies have postulated bats as one of the key reservoirs of coronaviruses (CoVs), and different CoVs have been detected in bats. So far, CoVs have not been found in bats in Sweden and we therefore tested whether they carry CoVs. In summer 2020, we sampled a total of 77 adult bats comprising 74 , 2 , and 1 bats in southern Sweden. Blood, saliva and feces were sampled, processed and subjected to a virus next-generation sequencing target enrichment protocol. An was detected and sequenced from feces of a adult female bat. Phylogenetic analysis of the almost complete virus genome revealed a close relationship with Finnish and Danish strains. This was the first finding of a CoV in bats in Sweden, and bats may play a role in the transmission cycle of CoVs in Sweden. Focused and targeted surveillance of CoVs in bats is warranted, with consideration of potential conflicts between public health and nature conservation required as many bat species in Europe are threatened and protected.
持续的新冠疫情激发了人们对可能参与病毒来回传播的宿主和物种的探索。研究推测蝙蝠是冠状病毒（CoV）的主要宿主之一，并且在蝙蝠中已检测到不同的冠状病毒。到目前为止，在瑞典的蝙蝠中尚未发现冠状病毒，因此我们测试了它们是否携带冠状病毒。2020年夏天，我们在瑞典南部共采集了77只成年蝙蝠的样本，其中包括74只、2只和1只蝙蝠。采集了血液、唾液和粪便样本，进行处理并采用病毒下一代测序目标富集方案。从一只成年雌性蝙蝠的粪便中检测到并测序了一种病毒。对几乎完整的病毒基因组进行系统发育分析发现，它与芬兰和丹麦的毒株关系密切。这是在瑞典蝙蝠中首次发现冠状病毒，蝙蝠可能在瑞典冠状病毒的传播循环中发挥作用。鉴于欧洲许多蝙蝠物种受到威胁并受到保护，在考虑公共卫生与自然保护之间潜在冲突的情况下，有必要对蝙蝠中的冠状病毒进行重点和有针对性的监测。
