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甲壳类动物模式生物夏威夷半黄褐新糠虾。

The crustacean model Parhyale hawaiensis.

作者信息

Paris Mathilde, Wolff Carsten, Patel Nipam H, Averof Michalis

机构信息

Institut de Génomique Fonctionnelle de Lyon, École Normale Supérieure de Lyon, Lyon, France; Centre National de la Recherche Scientifique (CNRS), France.

Marine Biological Laboratory, Woods Hole, MA, United States.

出版信息

Curr Top Dev Biol. 2022;147:199-230. doi: 10.1016/bs.ctdb.2022.02.001. Epub 2022 Mar 14.

Abstract

Arthropods are the most abundant and diverse animals on earth. Among them, pancrustaceans are an ancient and morphologically diverse group, comprising a wide range of aquatic and semi-aquatic crustaceans as well as the insects, which emerged from crustacean ancestors to colonize most terrestrial habitats. Within insects, Drosophila stands out as one of the most powerful animal models, making major contributions to our understanding of development, physiology and behavior. Given these attributes, crustaceans provide a fertile ground for exploring biological diversity through comparative studies. However, beyond insects, few crustaceans are developed sufficiently as experimental models to enable such studies. The marine amphipod Parhyale hawaiensis is currently the best established crustacean system, offering year-round accessibility to developmental stages, transgenic tools, genomic resources, and established genetics and imaging approaches. The Parhyale research community is small but diverse, investigating the evolution of development, regeneration, aspects of sensory biology, chronobiology, bioprocessing and ecotoxicology.

摘要

节肢动物是地球上数量最多、种类最丰富的动物。其中,泛甲壳动物是一个古老且形态多样的类群,包括各种水生和半水生甲壳动物以及昆虫,昆虫由甲壳动物祖先演化而来,占据了大多数陆地栖息地。在昆虫中,果蝇是最强大的动物模型之一,对我们理解发育、生理学和行为做出了重大贡献。鉴于这些特性,甲壳动物为通过比较研究探索生物多样性提供了丰富的素材。然而,除了昆虫之外,很少有甲壳动物被充分开发为实验模型以开展此类研究。海洋双足虾类夏威夷扁虾目前是最完善的甲壳动物系统,全年都可获取其发育阶段、转基因工具、基因组资源以及成熟的遗传学和成像方法。夏威夷扁虾研究群体规模虽小但种类多样,研究领域包括发育进化、再生、感觉生物学、生物钟学、生物处理和生态毒理学等方面。

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