Arthurs Jennifer R, Nordan Lisa M, Hultgren Brian H, Heckman Michael G, Martinez Dayana, Master Zubin, Shapiro Shane A
Center for Regenerative Medicine, Mayo Clinic, Jacksonville, FL, USA.
Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Jacksonville, FL, USA.
NPJ Regen Med. 2022 Mar 25;7(1):20. doi: 10.1038/s41536-022-00215-w.
Despite patient demand for stem cell therapies (SCTs) for musculoskeletal conditions, there remains limited research on why patients seek SCTs or their sources of information. We employ three questions into a consult intake form: (1) Why are you interested in stem cell treatment for your condition? (2) How did you find out about stem cell treatment for your condition? (3) Have you contacted a stem cell clinic? Responses analyzed, using a qualitative content analysis approach to identify themes reveal many patients seek SCTs to treat pain or delay surgery which may align with some current clinical evidence while other patients express motivations as expected outcomes (e.g., SCTs are better than standard of care or can regenerate tissue) which are not supported by current medical evidence. These differences suggests that patient-centered counseling may help patients by addressing misconceptions and increasing health literacy about expected outcomes of SCTs for treating musculoskeletal conditions.
尽管患者对用于肌肉骨骼疾病的干细胞疗法（SCTs）有需求，但关于患者寻求SCTs的原因或其信息来源的研究仍然有限。我们在咨询 intake 表格中设置了三个问题：（1）你为什么对你的病情进行干细胞治疗感兴趣？（2）你是如何得知针对你病情的干细胞治疗的？（3）你是否联系过干细胞诊所？使用定性内容分析方法对回复进行分析以确定主题，结果显示许多患者寻求SCTs来治疗疼痛或推迟手术，这可能与一些当前的临床证据相符，而其他患者则将动机表达为预期结果（例如，SCTs比标准治疗更好或可以再生组织），但这些并未得到当前医学证据的支持。这些差异表明，以患者为中心的咨询可能通过解决误解和提高患者对SCTs治疗肌肉骨骼疾病预期结果的健康素养来帮助患者。
