Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
Eur Arch Psychiatry Clin Neurosci. 2023 Jun;273(4):811-817. doi: 10.1007/s00406-022-01394-9. Epub 2022 Mar 25.
This article provides an overview and retrospective on metacognitive training for psychosis (MCT), which first appeared approximately 2 decades ago. We recount how our empirical understanding of psychosis at that time led to the first preliminary version of the program. We describe setbacks and challenges that led to major changes, including revisions to existing modules (e.g., more focus on metacognitive variables, particularly on decision confidence as one of the primary targets of treatment) and the creation of new modules addressing mood, as well as attempts to improve sustainability of effects via homework exercises and a smartphone app ( www.uke.de/mct_app ). We have also enhanced dissemination efforts by creating new culturally sensitive language versions and facilitating low-threshold training through e-learning courses ( www.uke.de/e-mct ). Finally, we discuss several meta-analyses on the efficacy of MCT that have been published over the last decade. While reviews were initially inconsistent, possibly reflecting the insufficient statistical power and lower design quality of the first MCT studies, more recent meta-analyses have confirmed the efficacy of MCT on positive symptoms, insight, and cognitive biases, which has led to the inclusion of MCT in some national treatment guidelines for schizophrenia.
本文对大约 20 年前出现的精神病认知训练(MCT)进行了概述和回顾。我们叙述了当时我们对精神病的实证理解如何导致了该项目的第一个初步版本。我们描述了导致重大变革的挫折和挑战,包括对现有模块的修订(例如,更关注元认知变量,特别是将决策信心作为主要治疗目标之一)以及创建新模块来解决情绪问题,以及尝试通过家庭作业练习和智能手机应用程序(www.uke.de/mct_app)来提高效果的可持续性。我们还通过创建新的文化敏感语言版本和通过电子学习课程(www.uke.de/e-mct)促进低门槛培训来增强传播力度。最后,我们讨论了过去十年中发表的几项关于 MCT 疗效的荟萃分析。虽然最初的综述结果不一致,这可能反映了最初的 MCT 研究在统计能力和设计质量上的不足,但最近的荟萃分析已经证实了 MCT 在阳性症状、洞察力和认知偏差方面的疗效,这使得 MCT 被纳入一些国家的精神分裂症治疗指南。