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基于深度学习的头皮 EEG 波型预测下腔出血继发癫痫的预测价值。

Prediction Value of Epilepsy Secondary to Inferior Cavity Hemorrhage Based on Scalp EEG Wave Pattern in Deep Learning.

机构信息

Department of Critical-care Medicine, Yongchuan Hospital Chongqing Medical University, Yongchuan, Chongqing 402160, China.

Department of Neurosurgery, Yongchuan Hospital Chongqing Medical University, Yongchuan, Chongqing 402160, China.

出版信息

J Healthc Eng. 2022 Mar 15;2022:2084276. doi: 10.1155/2022/2084276. eCollection 2022.

Abstract

OBJECTIVE

To search the predictive value of epilepsy secondary to acute subarachnoid hemorrhage (aSAH) based on EEG wave pattern in deep learning.

METHODS

A total of 156 cases of secondary epilepsy with lower cavity hemorrhage in our hospital were selected and divided into the late epilepsy group and the early epilepsy group according to seizure time, and the nonseizure group and the seizure group according to seizure condition. General data of patients were collected, the EEG types of each group were analyzed, and the disease recurrence rate, treatment effect, and symptom onset time were compared.

RESULTS

Rapid and slow and rapid blood flow velocity were the main abnormal manifestations of epilepsy secondary to inferior cavity hemorrhage, accounting for 33.3% and 18.6%, respectively. Compared with the seizure group, the proportion of type ii and type iii in the nonseizure group was higher, and the proportion of type ii and type iii in the early epilepsy group was higher than in the late epilepsy group ( < 0.05). The diagnostic accuracy, missed diagnosis rate, misdiagnosis rate, specificity, and sensitivity of the EEG wave pattern were 94.9%, 3.2%, 1.9%, 91.7%, and 96.2%, respectively. Compared with the early epilepsy group, the recurrence rate of type iii and type iv in the late epilepsy group was higher ( < 0.05). The effective rates of the attack group and the nonattack group were 72.7% and 97.0%, respectively. Compared with the attack group, the effective rate of the nonattack group was higher ( < 0.05). The effective rates of the early epilepsy group and the late epilepsy group were 91.7% and 85.0%, respectively. Compared with the late epilepsy group, the effective rate of the early epilepsy group was higher ( < 0.05). Compared with the early epilepsy group, the late epilepsy group had longer tonic-clonic seizures, atonic seizures, and absent seizures, and the difference between the groups was statistically significant ( < 0.05).

CONCLUSION

In aSAH secondary epilepsy disease prediction, based on indepth study of the scalp EEG wave type prediction, they play an important role, including aSAH high-risk secondary epilepsy wave types for V, III, and IV types, as well as early and late epilepsy associated with disease stage. Through the diagnosis method to predict the severity of disease, this builds a good foundation for clinical treatment. It is beneficial to improve the effective rate of treatment.

摘要

目的

基于深度学习探讨脑电图(EEG)波型对急性蛛网膜下腔出血(aSAH)继发癫痫的预测价值。

方法

选取我院收治的 156 例继发癫痫伴脑室内出血患者,根据发作时间分为迟发性癫痫组和早发性癫痫组,根据发作情况分为发作组和无发作组。收集患者的一般资料,分析各组 EEG 类型,比较疾病复发率、治疗效果、症状发作时间。

结果

迟发性癫痫伴脑室内出血的主要异常表现为快、慢血流速度,占比分别为 33.3%、18.6%。与发作组相比,无发作组的Ⅱ型和Ⅲ型比例较高,早发性癫痫组的Ⅱ型和Ⅲ型比例高于迟发性癫痫组(<0.05)。脑电图波型的诊断准确率、漏诊率、误诊率、特异度、敏感度分别为 94.9%、3.2%、1.9%、91.7%、96.2%。与早发性癫痫组相比,迟发性癫痫组Ⅲ型和Ⅳ型的复发率更高(<0.05)。发作组和无发作组的有效率分别为 72.7%、97.0%。与发作组相比,无发作组的有效率更高(<0.05)。早发性癫痫组和迟发性癫痫组的有效率分别为 91.7%、85.0%。与迟发性癫痫组相比,早发性癫痫组的有效率更高(<0.05)。与早发性癫痫组相比,迟发性癫痫组强直阵挛发作、失张力发作、失神发作持续时间更长,组间差异有统计学意义(<0.05)。

结论

在 aSAH 继发癫痫疾病预测中,基于深入研究头皮 EEG 波型预测,发挥着重要作用,包括 aSAH 高危继发癫痫波型 V、Ⅲ、Ⅳ型以及早发性、迟发性癫痫与疾病阶段相关。通过诊断方法预测疾病严重程度,为临床治疗奠定了良好基础,有利于提高治疗有效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fde/8941549/7798b7043fc8/JHE2022-2084276.001.jpg

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