Game of transmissions (GoT) of SARS-CoV-2: Second wave of COVID-19 is here in India.

Corona virus disease (COVID-19) pandemic had taken the humankind by surprise, yet the world laid out a historical battle against all the odds. Laboratory findings have never been so rapidly made available to common public and authorities. Experimental data on COVID-19 from across the globe was directly made accessible worldwide. The second wave of the pandemic in India caused unprecedented havoc and it can be stated that all the knowledge of the game of transmission of COVID-19 acquired and shared was not played with right precision and preparations. Rapid spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the second phase made us rethink if the choice of information given to the common people pertaining to the selective transmission restriction pathways with pressing concern on lethality were inadequate. Most of the governmental and non-governmental organizations (NGOs) including the World Health Organization (WHO) recommended droplet-based and airborne transmission restrictions as the major steps to control rapid spread of the virus. While, no caution was advised for other plausible pathways like sewage, wastewater-based and non-ventilated indoor air-based transmissions, which are still unknown or not well investigated, and are equally dangerous. The main focus of this article is to analyse the past development about SARS-CoV-2 transmission pathway related recommendation(s) provided by WHO and track the trajectory to alert all the concerning stakeholders and policymakers to rethink and to collect adequate scientific data before they recommend or neglect any specific or all the possible transmission pathways to control the spread of infectious agents further.