Hôpital du Sacré-Coeur de Montréal (CIUSSS-NIM), Montréal, QC, Canada.
Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
Transpl Int. 2022 Mar 10;35:10107. doi: 10.3389/ti.2022.10107. eCollection 2022.
Despite availability of selection criteria, different interpretations can lead to variability in the appreciation of donor eligibility with possible viable organs missed. Our primary objective was to test the perception of feasibility of potential organ donors through the survey of a small sample of external evaluators. Clinical scenarios summarizing 66 potential donors managed in the first year of our Organ Recovery Center were sent to four critical care physicians to evaluate the feasibility of the potential donors and the probability of organ procurement. Potential donors procuring at least one organ were identified in 55 of the 66 cases (83%). Unanimity was reached in 38 cases, encompassing 35 out of the 55 converted and 3 of the non-converted donors. The overall agreement was moderate (kappa = 0.60, 95% CI: 0.37-0.82). For the organs finally procured for transplantation, organ donation was predicted for the majority of the cases, but high discrepancy was present with the final outcome of organs not procured (particularly liver and kidney). The assessment of a potential donor is a complex dynamic process. In order to increase organ availability, standardized electronically clinical data, as well a "donor board" structure of decision might inform future systems.
尽管有选择标准,但不同的解释可能导致对供体资格的评估存在差异,从而可能错过有活力的器官。我们的主要目标是通过对一小部分外部评估者进行调查,来测试对潜在器官捐献者可行性的认识。 我们将总结了 66 名潜在供体在我们的器官回收中心成立后的第一年的临床情况的总结发送给了 4 名重症监护医生,以评估潜在供体的可行性和器官采集的可能性。 在 66 例中的 55 例(83%)中确定了至少有一个器官可采集的潜在供体。38 例达成了一致意见,其中包括 35 例已转换的和 3 例未转换的供体。总体一致性为中度(kappa = 0.60,95%置信区间:0.37-0.82)。对于最终用于移植的器官,大多数情况下预测会进行器官捐献,但对于未采集的器官(特别是肝脏和肾脏),最终结果存在很大差异。 对潜在供体的评估是一个复杂的动态过程。为了增加器官的可用性,标准化的电子临床数据以及决策的“供体委员会”结构可能会为未来的系统提供信息。