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环境过敏原控制在哮喘管理中的作用。

The role of environmental allergen control in the management of asthma.

作者信息

Kalayci Omer, Miligkos Michael, Pozo Beltrán César Fireth, El-Sayed Zeinab A, Gómez René Maximiliano, Hossny Elham, Le Souef Peter, Nieto Antonio, Phipatanakul Wanda, Pitrez Paulo Marcio, Xepapadaki Paraskevi, Jiu-Yao Wang, Papadopoulos Nikolaos G

机构信息

Pediatric Allergy and Asthma, Hacettepe University, School of Medicine, Ankara, Turkey.

First Department of Pediatrics, "Aghia Sophia" Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

World Allergy Organ J. 2022 Mar 8;15(3):100634. doi: 10.1016/j.waojou.2022.100634. eCollection 2022 Mar.

Abstract

Allergen exposure may exacerbate asthma symptoms in sensitized patients. Allergen reduction or avoidance measures have been widely utilized; however, there is ongoing controversy on the effectiveness of specific allergen control measures in the management of children with asthma. Often, allergen avoidance strategies are not recommended by guidelines because they can be complex or burdensome, although individual patients may benefit. Here we explore the potential for intervention against exposure to the major allergens implicated in asthma (ie, house dust mites, indoor molds, rodents, cockroaches, furry pets, and outdoor molds and pollens), and subsequent effects on asthma symptoms. We critically assess the available evidence regarding the clinical benefits of specific environmental control measures for each allergen. Finally, we underscore the need for standardized and multifaceted approaches in research and real-life settings, which would result in the identification of more personalized and beneficial prevention strategies.

摘要

变应原暴露可能会加重致敏患者的哮喘症状。减少或避免接触变应原的措施已被广泛应用;然而,在儿童哮喘管理中,特定变应原控制措施的有效性仍存在争议。通常,指南不推荐避免接触变应原的策略,因为这些策略可能复杂或繁琐,尽管个别患者可能从中受益。在此,我们探讨针对哮喘相关主要变应原(即屋尘螨、室内霉菌、啮齿动物、蟑螂、带毛宠物以及室外霉菌和花粉)暴露进行干预的可能性,以及对哮喘症状的后续影响。我们严格评估了关于每种变应原的特定环境控制措施临床益处的现有证据。最后,我们强调在研究和实际生活环境中需要采用标准化和多方面的方法,这将有助于确定更具个性化和有益的预防策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e499/8917313/bc55560f4468/gr1.jpg

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