日本野生梅花鹿（Cervus nippon）中新的细小副粘病毒的基因组特征和流行情况。
Genomic characterization and the prevalence of a novel copiparvovirus in wild sika deer (Cervus nippon) in Japan.
机构信息
Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke, Tochigi 329-0498, Japan.
Iida Public Health Center, Iida, Nagano 395-0034, Japan.
出版信息
Virus Res. 2022 Jun;314:198749. doi: 10.1016/j.virusres.2022.198749. Epub 2022 Mar 21.
A preliminary metagenomic analysis of the virome of wild sika deer (Cervus nippon) blood in Japan resulted in the identification of a novel parvovirus. The virus was closest, but only 44.7-60.7% identical to 17 reported strains belonging to the genus Copiparvovirus within the subfamily Parvovirinae, over the near-entire genomic sequence. The sika deer copiparvovirus DNA was detected in 15% (31/206) of sika deer captured in 7 prefectures of Japan, and a region-dependent prevalence of 0-66.7% was noted, with a biased distribution in the southern part of Japan. The observed biased distribution of sika deer copiparvovirus may be due to the habitat density of deer and the number of ticks, which might play a role in the transmission of the virus.
对日本野生梅花鹿血液病毒组的初步宏基因组分析鉴定出一种新型细小病毒。该病毒与近全长基因组序列上仅 44.7-60.7%同源的 17 株已报道的科氏细小病毒属成员最为接近，属于细小病毒亚科细小病毒科。在日本 7 个县捕获的 206 只梅花鹿中，有 15%（31/206）检测到了鹿微小病毒 DNA，在不同地区的流行率为 0-66.7%，在日本南部呈偏分布。鹿微小病毒的这种观察到的偏分布可能是由于鹿的栖息地密度和蜱的数量，这可能在病毒的传播中起作用。
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