Tamamura-Andoh Yukino, Tanaka Nobuyuki, Sato Keisuke, Mizuno Yoshino, Arai Nobuo, Watanabe-Yanai Ayako, Akiba Masato, Kusumoto Masahiro
Division of Bacterial and Parasitic Disease, National Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
Tottori Station, National Livestock Breeding Center, 14 Idekami, Kotoura, Tohaku, Tottori 689-2511, Japan.
J Vet Med Sci. 2021 May 9;83(5):754-758. doi: 10.1292/jvms.21-0005. Epub 2021 Mar 11.
We examined the antimicrobial susceptibility of 848 Escherichia coli isolates from 237 feces samples of wild sika deer (Cervus nippon) captured between 2016 and 2019 in 39 of the 47 prefectures of Japan. Five of the 237 wild sika deer (2.1%) carried E. coli with resistance to at least one antimicrobial, and all the resistant isolates showed resistance to tetracycline. The resistant isolates contained antimicrobial resistance genes that were similar to those in E. coli derived from humans and farm animals. Although wild sika deer are not currently likely to be a source for the transmission of antimicrobial resistance in Japan, they can potentially mediate antimicrobial resistance spread by coming into contact with humans, animals, and their surroundings.
我们检测了2016年至2019年间在日本47个都道府县中的39个地区捕获的237份野生梅花鹿（日本鹿）粪便样本中848株大肠杆菌的抗菌药敏性。237只野生梅花鹿中有5只（2.1%）携带对至少一种抗菌药物耐药的大肠杆菌，所有耐药菌株均对四环素耐药。这些耐药菌株所含的抗菌耐药基因与源自人类和农场动物的大肠杆菌中的基因相似。虽然目前野生梅花鹿在日本不太可能成为抗菌药物耐药性传播的源头，但它们有可能通过与人类、动物及其周围环境接触而介导抗菌药物耐药性的传播。
