From the Palm Beach County Medical Examiner Office, retired, West Palm Beach, Florida (Bell).
The Department of Biostatistics, College of American Pathologists, Northfield, Illinois (Long).
Arch Pathol Lab Med. 2022 Dec 1;146(12):1486-1495. doi: 10.5858/arpa.2021-0287-OA.
CONTEXT.—: Organ weights are an essential part of autopsy analysis. Deviations from normal organ weights provide important clues to disease processes. The assessment of normal organ weights depends on reliable reference tables, but most widely available reference tables are based on data that are either decades old or derived from relatively small sample sizes.
OBJECTIVE.—: To provide an updated reference table of organ weights based on contemporary sources and a large sample size.
DESIGN.—: Organ weights from 4197 carefully screened autopsies performed on adults at the Palm Beach County Medical Examiner's Office in West Palm Beach, Florida, and the Mayo Clinic Hospital in Rochester, Minnesota.
RESULTS.—: Height and body weight data in this study reflect the well-recognized increases in both variables, but most particularly in body weight, seen during the last decades. The study data show a strong positive association between organ weight and body weight for the heart, liver, and spleen. There is a similar but weaker association between body weight and the weight of the lungs and kidneys. Brain weight is independent of body weight but shows a strong negative association with age. Even when controlling for body weight, men's organs are heavier, except for the weight of the liver, which is comparable in men and women. These associations are in agreement with the findings of previous studies. The current study suggests that, for some of the commonly weighed organs, there has been an increase in median organ weight when compared with existing references.
CONCLUSIONS.—: The tables presented here provide an updated reference that should prove useful to autopsy pathologists in the forensic and hospital settings.
器官重量是尸检分析的重要组成部分。器官重量的偏差为疾病过程提供了重要线索。正常器官重量的评估取决于可靠的参考表，但大多数广泛可用的参考表基于的是几十年前的数据，或者是从相对较小的样本量中得出的。
提供一份基于当代资料和大样本量的更新的器官重量参考表。
佛罗里达州西棕榈滩棕榈滩县法医办公室和明尼苏达州罗切斯特市梅奥诊所医院进行的 4197 例精心筛选的成人尸检中获取的器官重量。
本研究中的身高和体重数据反映了过去几十年中这两个变量的公认增长，特别是体重的增长。研究数据显示，心脏、肝脏和脾脏的器官重量与体重之间存在强烈的正相关。肺和肾脏的体重与体重之间也存在类似但较弱的关联。脑重量与体重无关，但与年龄呈强烈负相关。即使在控制体重的情况下，男性的器官也更重，除了男性和女性的肝脏重量相当。这些关联与先前研究的发现一致。本研究表明，与一些常见的称重器官相比，与现有参考值相比，其器官重量中位数有所增加。
这里提供的表格提供了一个更新的参考，应该对法医和医院环境中的尸检病理学家有用。
