Department of Psychiatry, Government Medical College & Hospital, Chandigarh, India.
Indian J Med Res. 2021 Mar;154(3):476-482. doi: 10.4103/ijmr.IJMR_930_19.
BACKGROUND & OBJECTIVES: Prevalence of autism spectrum disorder (ASD) has been reportedly on the rise in western literature. However, accurate data from India are not available. The present study was planned to assess the community-based prevalence of ASD in Chandigarh, India.
This study was a two-stage survey of representative child population of Chandigarh using stratified random sampling technique, covering 8820 children between the ages 1.5 and 10 yr. Proportionate population from urban (82.3%), rural (4.3%) and slum area (13.4%) were included in the study and screened using Chandigarh autism screening instrument (CASI). Thirty two children scored above cut-off, of whom two had shifted to other places before they could be assessed and 30 were assessed in detail. Detailed assessment was done using Autism Diagnostic Interview-Revised and Childhood Autism Rating Scale-2; diagnosis was made according to the Diagnostic and Statistical Manual-5. Nineteen were diagnosed with ASD.
Of the 8451 children screened between the age group of one and a half to 10 yr, 19 (10 boys and 9 girls) were diagnosed as ASD, thus the prevalence of ASD was found to be 2.25 per 1000 (0.69-5.19, 95% confidence interval) children in Chandigarh. No child below the cut-off on the screening instrument was diagnosed as ASD.
INTERPRETATION & CONCLUSIONS: The results suggest that the prevalence of ASD in Chandigarh was in tandem with other reports from across India and was lower than western countries.
自闭症谱系障碍(ASD)的发病率在西方文献中报道呈上升趋势。然而,印度没有准确的数据。本研究旨在评估印度昌迪加尔的自闭症社区患病率。
本研究采用分层随机抽样技术,对昌迪加尔的代表性儿童人群进行了两阶段调查,覆盖了 8820 名 1.5 至 10 岁的儿童。来自城市(82.3%)、农村(4.3%)和贫民窟地区(13.4%)的比例人群被纳入研究,并使用昌迪加尔自闭症筛查工具(CASI)进行筛查。32 名儿童的得分超过了临界值,其中 2 名在评估前已搬至其他地方,30 名儿童接受了详细评估。详细评估使用自闭症诊断访谈修订版和儿童自闭症评定量表-2 进行;根据《精神障碍诊断与统计手册-5》进行诊断。19 名儿童被诊断为 ASD。
在年龄为 1.5 至 10 岁的 8451 名儿童中,有 19 名(10 名男孩和 9 名女孩)被诊断为 ASD,因此昌迪加尔的 ASD 患病率为每 1000 名儿童 2.25 例(95%置信区间为 0.69-5.19)。没有一个在筛查工具上低于临界值的儿童被诊断为 ASD。
结果表明,昌迪加尔的 ASD 患病率与印度其他地区的报告一致,且低于西方国家。