自闭症谱系障碍的流行病学：2014年以来全球患病率估计综述
Epidemiology of Autism Spectrum Disorders: A Review of Worldwide Prevalence Estimates Since 2014.
作者信息
Chiarotti Flavia, Venerosi Aldina
机构信息
Reference Center for the Behavioural Sciences and Mental Health, Italian National Institute of Health, 00161 Rome, Italy.
出版信息
Brain Sci. 2020 May 1;10(5):274. doi: 10.3390/brainsci10050274.
Abstract
The prevalence of Autism Spectrum Disorder (ASD) has increased dramatically in recent decades, supporting the claim of an autism epidemic. Systematic monitoring of ASD allows estimating prevalence and identifying potential sources of variation over time and geographical areas. At present, ASD prevalence estimates are available worldwide, coming either from surveillance systems using existing health and educational databases or from population studies specifically performed. In the present article, we present a review of the ASD prevalence estimates published since 2014. Data confirm a high variability in prevalence across the world, likely due to methodological differences in case detection, and the consistent increase of prevalence estimates within each geographical area.
摘要
近几十年来，自闭症谱系障碍（ASD）的患病率急剧上升，这支持了自闭症流行的说法。对ASD进行系统监测有助于估计患病率，并确定随时间和地理区域变化的潜在差异来源。目前，全球范围内都有ASD患病率的估计数据，这些数据要么来自使用现有健康和教育数据库的监测系统，要么来自专门开展的人群研究。在本文中，我们对2014年以来发表的ASD患病率估计进行了综述。数据证实，全球患病率存在很大差异，这可能是由于病例检测方法的不同，并且每个地理区域内患病率估计值都在持续上升。
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2
A Conceptual Framework for Understanding the Cultural and Contextual Factors on Autism Across the Globe.理解全球自闭症文化和情境因素的概念框架。
Autism Res. 2020 Jul;13(7):1029-1050. doi: 10.1002/aur.2276. Epub 2020 Feb 21.
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