Centre for Autism, School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.
Department of Psychology, Ben Gurion University of the Negev, Beer-Sheva, Israel.
Autism Res. 2017 Oct;10(10):1597-1605. doi: 10.1002/aur.1812. Epub 2017 May 25.
Despite housing ∼18% of the world's population, India does not yet have an estimate of prevalence of autism. This study was carried out to estimate the prevalence of autism in a selected population of school-children in India. N = 11,849 children (mean age = 5.9 [SD = 1.3], 39.5% females) were selected from various school types from three boroughs in Kolkata, India. Parents/caregivers and teachers filled in the social and communication disorders checklist (SCDC). Children meeting cutoff on parent-reported SCDC were followed up with the social communication questionnaire (SCQ). SCQ-positive children were administered the autism diagnostic observation schedule (ADOS). Teacher report on SCDC was available on all 11,849 children. Parent-report SCDC scores were obtained for 5,947 children. Mean scores on teacher SCDC were significantly lower than parent SCDC. Out of 1,247 SCDC-positive children, 882 answered the SCQ, of whom 124 met the cutoff score of 15. Six of these children met criteria for autism, autism spectrum disorder (ASD), or broader autism spectrum on the ADOS. The weighted estimate of supra-threshold SCQ scores was 3.54% (CI: 2.88-4.3%). The weighted prevalence estimate of positive scores (for broader autism spectrum + ASD + autism) was 0.23% (0.07-0.46%). As ∼20% children in this state are known to be out of the school system, and ASD prevalence is likely to be higher in this group, this estimate is likely to represent the lower-bound of the true prevalence. This study provides preliminary data on the prevalence of broader-spectrum autism and supra-threshold autistic traits in a population sample of school children in Eastern India. Autism Res 2017, 10: 1597-1605. ©2017 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research.
尽管印度仅占世界人口的 18%，但目前仍未对其自闭症的流行率进行估计。本研究旨在对印度特定地区学龄儿童自闭症的流行率进行估计。从印度加尔各答三个区的不同类型学校中选择了 11849 名儿童（平均年龄为 5.9[SD=1.3]，女性占 39.5%）。父母/照顾者和教师填写了社交和沟通障碍检查表（SCDC）。在父母报告的 SCDC 达到截止值的儿童中，采用社交沟通问卷（SCQ）进行随访。SCQ 阳性的儿童进行了自闭症诊断观察量表（ADOS）评估。所有 11849 名儿童均有教师报告的 SCDC，其中 5947 名儿童的家长报告了 SCDC 评分。教师 SCDC 的平均评分明显低于家长 SCDC。在 1247 名 SCDC 阳性儿童中，有 882 名回答了 SCQ，其中 124 名达到了 15 分的截止值。这 124 名儿童中有 6 名符合 ADOS 自闭症、自闭症谱系障碍（ASD）或广泛自闭症的标准。高于阈值的 SCQ 评分的加权估计值为 3.54%（95%CI：2.88-4.3%）。阳性评分（广泛自闭症+ASD+自闭症）的加权流行率估计值为 0.23%（95%CI：0.07-0.46%）。由于该州约 20%的儿童已知不在学校系统中，且该组的自闭症患病率可能更高，因此该估计值可能代表了真实患病率的下限。本研究为印度东部学龄儿童群体样本中更广泛的自闭症谱系和高于阈值的自闭症特征的流行率提供了初步数据。自闭症研究 2017, 10: 1597-1605。©2017 作者 自闭症研究由 Wiley Periodicals, Inc. 代表国际自闭症研究协会出版。
