University of Cologne Faculty of Medicine, Department of Gynecology and Obstetrics, University of Cologne, Cologne, Germany;
Breast Cancer Center, St. Franziskus-Hospital, Münster, Germany.
Anticancer Res. 2022 Apr;42(4):1925-1932. doi: 10.21873/anticanres.15670.
BACKGROUND/AIM: The combination of pre-surgical clip placement and hook-wire guided surgery is considered the gold standard for adequately locating non-palpable lesions during breast conserving surgery. After surgical removal of the segment, radiography is required to confirm clip removal, increasing surgical time, post-surgical complication rates, and cost.
We performed a retrospective analysis, using the Faxitron in-theater specimen radiography system, of the following primary endpoints: surgical time and complication rates. The secondary endpoints were cost effectiveness and clip-location rates. The Control cohort included breast conserving surgery patients prior to May 2019 (n=150) and the Validation cohort included breast conserving surgery patients after May 2019 (n=53).
The analysis showed an improvement in surgical time when using the Faxitron system, which is directly linked to a benefit in cost effectiveness. A numerical benefit in complication rates was also shown. A subgroup analysis showed a significant advantage in surgical time for breast conserving surgery plus sentinel node biopsy and open breast biopsies.
Use of the Faxitron system significantly reduces surgical time, which increases cost efficiency while maintaining a low complication rate.
背景/目的：术前夹放置和钩丝引导手术的联合被认为是在保乳手术中充分定位不可触及病变的金标准。在切除节段后，需要进行放射检查以确认夹移除，这增加了手术时间、术后并发症发生率和成本。
我们使用 Faxitron 术中标本放射照相系统对以下主要终点进行回顾性分析：手术时间和并发症发生率。次要终点是成本效益和夹定位率。对照组包括 2019 年 5 月前的保乳手术患者（n=150），验证组包括 2019 年 5 月后的保乳手术患者（n=53）。
分析显示，使用 Faxitron 系统可缩短手术时间，这与成本效益的提高直接相关。还显示出并发症发生率的数值优势。亚组分析显示，保乳手术加前哨淋巴结活检和开放性乳房活检的手术时间有显著优势。
使用 Faxitron 系统可显著缩短手术时间，提高成本效益，同时保持低并发症率。
