Jean François Arnaud Matthieu, Arsandaux Julie, Montagni Ilaria, Collet Ophélie, Fatséas Mélina, Auriacombe Marc, Ramos-Quiroga Josep Antoni, Côté Sylvana M, Tzourio Christophe, Galéra Cédric
Dr Jean Eric Techer Hospital, Department of Psychiatry, Calais, France.
University of Bordeaux, Bordeaux, France.
Eur Psychiatry. 2022 Mar 29;65(1):1-18. doi: 10.1192/j.eurpsy.2022.14.
Cannabis use in university students is associated with academic achievement failure and health issues. The objective of the study was to evaluate the association between attention deficit hyperactivity disorder (ADHD) symptoms and cannabis use after 1 year among students according to previous cannabis use.
Students in France were recruited from February 2013 to July 2020 in the i-Share cohort. 4,270 participants were included (2,135 who never used cannabis at inclusion and 2,135 who did). The Adult ADHD Self-Report Scale (ASRS) was used to assess ADHD symptoms at inclusion. Cannabis use frequency was evaluated 1 year after inclusion. Multinomial regressions were conducted to assess the association between inclusion ADHD symptoms and cannabis use after 1 year.
Increase in ASRS scores was linked with a greater probability to use cannabis after 1 year and to have a higher cannabis use frequency (once a year—once a month adjusted odds ratio [OR]: 1.24 (1.15–1.34), more than once a month adjusted OR: 1.43 (1.27–1.61)). Among participants who never used cannabis at inclusion, this association disappeared (once a year—once a month adjusted OR: 1.15 (0.95–1.39), more than once a month adjusted OR: 1.16 (0.67–2)) but remained in participants who ever used cannabis at inclusion (once a year—once a month adjusted OR: 1.17 (1.06–1.29), more than once a month adjusted OR: 1.35 (1.18–1.55)).
High levels of ADHD symptoms in students could lead to continued cannabis use rather than new initiations.
大学生使用大麻与学业成绩不佳和健康问题有关。本研究的目的是根据学生以前的大麻使用情况，评估注意缺陷多动障碍（ADHD）症状与1年后大麻使用之间的关联。
2013年2月至2020年7月在法国i-Share队列中招募学生。纳入4270名参与者（2135名在纳入时从未使用过大麻，2135名使用过）。在纳入时使用成人ADHD自我报告量表（ASRS）评估ADHD症状。在纳入1年后评估大麻使用频率。进行多项回归分析以评估纳入时的ADHD症状与1年后大麻使用之间的关联。
ASRS评分增加与1年后使用大麻的可能性更大以及大麻使用频率更高相关（每年一次至每月一次调整优势比[OR]：1.24（1.15 - 1.34），每月多次调整OR：1.43（1.27 - 1.61））。在纳入时从未使用过大麻的参与者中，这种关联消失了（每年一次至每月一次调整OR：1.15（0.95 - 1.39），每月多次调整OR：1.16（0.67 - 2）），但在纳入时曾使用过大麻的参与者中仍然存在（每年一次至每月一次调整OR：1.17（1.06 - 1.29），每月多次调整OR：1.35（1.18 - 1.55））。
学生中高水平的ADHD症状可能导致持续使用大麻，而非开始使用大麻。
