Department of Philosophy, University of Bergen, Bergen, Norway.
Front Public Health. 2024 Jan 5;11:1268339. doi: 10.3389/fpubh.2023.1268339. eCollection 2023.
There are well-established literatures documenting the associations between mental disorders and unhealthy behaviors such as poor diet quality, sedentary behavior, and cannabis and tobacco use. Few studies have attempted to understand the respective findings in light of each other, however.
The purpose of this review was to assemble comparable data for each behavior-disorder association and assess the associations in terms of their overall strength. The review aimed to include a representative, but not exhaustive, range of studies that would allow for explorative comparisons.
Eligible studies were identified via Pubmed searches and citation searching, restricted to publications no older than 2015 written in English. To obtain comparable data, only studies that reported findings as odds ratios were included, and risk of bias related to study samples, behavioral measurement disparities, and control variables was assessed via sensitivity analyses. Findings for each disorder were compared on the basis of different measures of central tendency.
From 3,682 records, 294 studies were included. The review found evidence of associations between each of the four unhealthy behaviors and psychosis, depression, anxiety, bipolar disorder, attention-deficit/hyperactivity disorder (ADHD), and post-traumatic stress disorder (PTSD), while personality disorder was only investigated in relation to cannabis and tobacco use. In overall comparison, the associations were generally of similar strength, and only the association between cannabis use and personality disorder was exceptional in terms of being significantly stronger than its counterparts across disorders and across behaviors. Analyses of bias risk identified some influence from behavioral measurement disparities and lack of adequate statistical control, but findings were generally robust across a range of sensitivity analyses.
This explorative and comparative review found that poor diet quality, sedentary behavior, and cannabis and tobacco use are about equally strongly associated with a range of different mental disorders. Given the general nature of these associations, we should probably understand them to reflect a general and shared etiology. However, the findings in this review should be regarded as tentative until confirmed by more comprehensive investigations.
有大量文献记录了精神障碍与不健康行为之间的关联,例如饮食质量差、久坐行为以及使用大麻和烟草。然而,很少有研究试图相互参照各自的研究结果。
本综述的目的是为每种行为-障碍关联汇集可比数据,并根据其整体强度评估关联。该综述旨在纳入具有代表性但非详尽的一系列研究,以便进行探索性比较。
通过 Pubmed 搜索和引文搜索,限制在 2015 年以前发表的英文文献,确定符合条件的研究。为了获得可比数据,仅纳入报告比值比结果的研究,并通过敏感性分析评估与研究样本、行为测量差异和控制变量相关的偏倚风险。基于不同的中心趋势测量方法,对每种障碍的发现进行比较。
从 3682 条记录中,纳入了 294 项研究。该综述发现,四种不健康行为中的每一种都与精神病、抑郁症、焦虑症、双相情感障碍、注意缺陷多动障碍(ADHD)和创伤后应激障碍(PTSD)之间存在关联,而人格障碍仅与大麻和烟草使用有关。总体比较,这些关联的强度大致相当,只有大麻使用与人格障碍之间的关联例外,它在跨障碍和跨行为的所有关联中都显著更强。偏倚风险分析发现,行为测量差异和缺乏充分的统计控制存在一些影响,但在一系列敏感性分析中,结果普遍稳健。
本探索性和比较性综述发现,饮食质量差、久坐行为以及使用大麻和烟草与一系列不同的精神障碍密切相关。鉴于这些关联的普遍性,我们可能应该将其理解为反映一种普遍而共同的病因。然而,在更全面的调查证实之前,本综述中的发现应被视为暂定的。