Department of Oncology, Kaiser Permanente San Jose Medical Center, San Jose, CA.
Perm J. 2021 May 12;25:20.262. doi: 10.7812/TPP/20.262.
The landmark value of mean corpuscular volume (MCV) in the diagnosis and classification of anemias has been established more than a century ago. In contrast, the importance of MCV assessment in patients with elevated hemoglobin and hematocrit is not nearly as appreciated.
This case describes a patient who exhibited long-standing macrocytosis (elevated MCV) that contributed to elevated hemoglobin and hematocrit levels thus mimicking a diagnosis of polycythemia vera.
The case demonstrates that discounting the MCV effect on hemoglobin/hematocrit levels can lead to potential errors in interpretation of blood tests and misdiagnosis.
一个多世纪以前，平均红细胞体积（MCV）在贫血的诊断和分类中的里程碑价值就已经确立。相比之下，MCV 评估在血红蛋白和血细胞比容升高的患者中的重要性还远未被充分认识。
本病例描述了一位长期存在大细胞性贫血（MCV 升高）的患者，导致血红蛋白和血细胞比容水平升高，从而模拟真性红细胞增多症的诊断。
本病例表明，忽略 MCV 对血红蛋白/血细胞比容水平的影响可能导致血液检测结果解读出现潜在错误和误诊。
