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迷走神经刺激术治疗肿瘤相关性癫痫:是否合理?

Vagus Nerve Stimulation for Tumor-Related Epilepsy: Does It Make Sense?

机构信息

Department of Neurology, Kaiser Permanente, Los Angeles Medical Center, Los Angeles, CA.

出版信息

Perm J. 2021 Jun 9;25:20.276. doi: 10.7812/TPP/20.276.

Abstract

Seizure is a common presenting symptom for those with brain tumor due to its unique pathogenesis. Several choices of antiepileptic drug are available to use, but some patients can still go on to develop tumor-related refractory epilepsy. Vagus nerve stimulation is becoming a popular option for those with medical refractory epilepsy but no brain tumor due to its effectiveness. There are very few studies available that address the topic of using vagus nerve stimulation for tumor-related epilepsy. Here we discuss the evidence of using vagus nerve stimulation for refractory tumor-related epilepsy and its challenges and gaps moving forward.

摘要

癫痫发作是脑肿瘤患者的常见症状,其发病机制独特。有几种抗癫痫药物可供选择,但有些患者仍会发展为与肿瘤相关的难治性癫痫。由于其有效性,迷走神经刺激术成为无脑瘤但药物难治性癫痫患者的热门选择。目前很少有研究涉及迷走神经刺激术治疗与肿瘤相关的癫痫。在这里,我们讨论了使用迷走神经刺激术治疗难治性肿瘤相关癫痫的证据,以及未来的挑战和空白。

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