乳腺癌患者放射治疗后出现膈神经麻痹。
Phrenic Nerve Palsy Following Radiation Therapy for Patient With Breast Cancer.
机构信息
Michigan State University Department of Medicine, Sparrow Hospital, Lansing, MI.
出版信息
Perm J. 2021 Dec 10;25:20.313. doi: 10.7812/TPP/20.313.
INTRODUCTION
Breast cancer is the most common malignancy affecting women in US today. Radiotherapy used after breast-conserving surgery has been shown to decrease local recurrence while minimizing side effects. Peripheral neuropathy remains a common and well-known complication of radiotherapy for breast cancer; however, it is rarely associated with phrenic nerve palsy after treatment of breast cancer.
CASE PRESENTATION
We describe a 66-year-old woman with a significant past medical history of chronic obstructive pulmonary disease and asthma who presented with hypoxia after completing radiotherapy for breast cancer. After ruling out other causes of hypoxemia, the patient was diagnosed with diaphragmatic dysfunction, likely caused by phrenic nerve palsy resulting from radiotherapy-induced neuropathy after treatment of breast cancer.
CONCLUSION
This case is the first reported incidence of phrenic nerve palsy resulting from radiotherapy for breast cancer.
简介
乳腺癌是当今美国影响女性最常见的恶性肿瘤。保乳手术后进行放疗已被证明可以降低局部复发率，同时最大限度地减少副作用。周围神经病变仍然是乳腺癌放疗的常见且众所周知的并发症; 然而，在治疗乳腺癌后很少与膈神经麻痹相关。
病例介绍
我们描述了一位 66 岁的女性，她有慢性阻塞性肺疾病和哮喘的重要既往病史，在完成乳腺癌放疗后出现缺氧。在排除低氧血症的其他原因后，患者被诊断为膈肌功能障碍，可能是由乳腺癌放疗引起的放射性神经病导致的膈神经麻痹引起的。
结论
本例是首例报道的乳腺癌放疗引起的膈神经麻痹病例。
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