Medical Faculty, Department of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
Radiat Oncol. 2020 Mar 30;15(1):71. doi: 10.1186/s13014-020-01501-x.
Radiation therapy is an integral part of the multidisciplinary management of breast cancer. Regional lymph node irradiation in younger trials seems to provide superior target coverage as well as a reduction in long-term toxicity resulting in a small benefit in the overall survival rate. For partial breast irradiation there are now two large trials available which support the role of partial breast irradiation in low risk breast cancer patients. Multiple randomized trials have established that a sequentially applied dose to the tumor bed improves local control with the cost of worse cosmetic results.
放射治疗是乳腺癌多学科综合管理的一个组成部分。在早期的试验中，区域淋巴结照射似乎能更好地覆盖靶区，并降低长期毒性，从而使总生存率略有提高。对于部分乳房照射，现在有两项大型试验支持部分乳房照射在低危乳腺癌患者中的作用。多项随机试验已经证实，肿瘤床序贯给予剂量可以提高局部控制率，但代价是美容效果更差。
