Department of Cardiac Surgery, Santa Maria Hospital. GVM Care & Research, Bari, Italy.
Dipartimento Scienze Mediche e Chirurgiche, Università di Foggia, Italy.
Eur J Cardiothorac Surg. 2022 Aug 3;62(3). doi: 10.1093/ejcts/ezac167.
The need for concomitant tricuspid surgery in patients who need mitral valve surgery casts doubt on its feasibility via a minimally invasive approach. Our goal was to evaluate the short-term outcomes of patients undergoing concomitant mitral and tricuspid valve surgery either with a standard full sternotomy (full-MTS) or a minimally invasive approach (mini-MTS).
The outcomes of patients who had combined mitral and tricuspid valve surgery in 11 centres were retrospectively evaluated. The primary outcome was the incidence of 30-day mortality. A propensity score matched cohort was selected to create 2 comparable groups stratified by surgery (valve replacement or repair).
During the study period, 1048 consecutive patients had combined mitral and tricuspid valve surgery (730 full-MTS, 318 mini-MTS). The matching procedure paired 192 full-MTS to 192 mini-MTS procedures. After matching, mini-MTS was associated with longer cardiopulmonary bypass [123 min, standard deviation (SD) 46, vs 102 min, SD 36, P = 0.001] and cross-clamping times (89 min, SD 34, vs 78 min, SD 29, P = 0.003). Although the hospital length of stay was shorter (8 days, interquartile range 7-12 vs 9 days, interquartile range 7-14, P = 0.034) with mini-MTS before matching, this difference disappeared after matching. No differences in other major complications or in 30-day mortality were observed: 48 deaths (4.6%), 36 of which (4.9%) occurred in patients who had a full-MTS and 12 (3.8%), in patients who had a mini-MTS (4.7% in both approaches paired by propensity).
The mini-MTS approach proved to be safe and effective in patients requiring concomitant mitral and tricuspid surgery. We could not demonstrate any difference in short-term outcomes between the 2 surgical approaches, indicating that there is not a preferred surgical approach.
对于需要二尖瓣手术的患者,三尖瓣同期手术的必要性使得微创方法的可行性受到质疑。我们的目标是评估通过标准胸骨正中切开术(全正中切开术,full-MTS)或微创方法(微创正中切开术,mini-MTS)进行同期二尖瓣和三尖瓣手术的患者的短期结果。
回顾性评估了 11 个中心接受联合二尖瓣和三尖瓣手术的患者的结果。主要结局是 30 天死亡率的发生率。选择倾向评分匹配队列来创建按手术(瓣膜置换或修复)分层的 2 个可比组。
在研究期间,1048 例连续患者接受了联合二尖瓣和三尖瓣手术(730 例 full-MTS,318 例 mini-MTS)。匹配程序将 192 例 full-MTS 与 192 例 mini-MTS 手术配对。匹配后,mini-MTS 与更长的体外循环时间相关[123 分钟,标准差(SD)46,与 102 分钟,SD 36,P = 0.001]和夹闭时间(89 分钟,SD 34,与 78 分钟,SD 29,P = 0.003)。尽管 mini-MTS 术前住院时间较短(8 天,四分位距 7-12 与 9 天,四分位距 7-14,P = 0.034),但匹配后这种差异消失了。在其他主要并发症或 30 天死亡率方面没有观察到差异:48 例死亡(4.6%),其中 36 例(4.9%)发生在接受 full-MTS 的患者中,12 例(3.8%)发生在接受 mini-MTS 的患者中(两种方法配对的 30 天死亡率均为 4.7%)。
微创正中切开术在需要同期二尖瓣和三尖瓣手术的患者中被证明是安全有效的。我们无法证明两种手术方法之间的短期结果存在差异,这表明没有首选的手术方法。