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双侧肾嗜酸细胞瘤:主动监测与部分肾切除术

Bilateral Renal Oncocytoma: Active Surveillance Versus Partial Nephrectomy.

作者信息

Sathe Abha, Lindars David, Sathe Pranav, Nallapareddy Rithvik, Grennan Tim

机构信息

Urology, California Northstate University College of Medicine, Elk Grove, USA.

Hematology and Medical Oncology, California Northstate University College of Medicine, Elk Grove, USA.

出版信息

Cureus. 2022 Feb 16;14(2):e22303. doi: 10.7759/cureus.22303. eCollection 2022 Feb.

Abstract

Renal oncocytomas (ROs) are benign tumors comprising 16% of renal masses. Due to the overlapping phenotypes seen in RO and chromophobe renal cell carcinoma (RCC) and lack of specific clinical and laboratory characteristics of RO, physicians face a challenge when arriving at a definitive diagnosis of RO. ROs additionally appear indistinct from RCCs on CT scan, contributing further to the difficulty of arriving at a clear diagnosis of RO.  This is a case report of a 66-year-old man who presented with flank pain found to be related to bilateral ROs and underwent bilateral partial nephrectomies. ROs are benign small renal masses that often pose a diagnostic challenge since preoperative diagnosis can be difficult to achieve. Given advancements in technology, active surveillance with core renal biopsy is a promising approach to accurately diagnose and manage ROs conservatively. The application of these techniques has wide-reaching implications for patients and physicians by reducing the need for a potentially harmful surgery and creating a cost-effective way to manage a diagnosis.

摘要

肾嗜酸细胞瘤(ROs)是良性肿瘤,占肾肿块的16%。由于RO与嫌色肾细胞癌(RCC)存在重叠的表型,且RO缺乏特异性的临床和实验室特征,医生在对RO做出明确诊断时面临挑战。此外,RO在CT扫描上与RCC难以区分,这进一步增加了明确诊断RO的难度。本文报告了一例66岁男性患者,因胁腹痛就诊,发现与双侧RO有关,并接受了双侧部分肾切除术。RO是良性小肾肿块,由于术前难以诊断,常常带来诊断挑战。随着技术的进步,通过肾芯活检进行主动监测是一种有前景的方法,可准确诊断并保守管理RO。这些技术的应用对患者和医生具有广泛影响,可减少潜在有害手术的需求,并创造一种经济有效的诊断管理方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28f/8933140/eebbea00f5ac/cureus-0014-00000022303-i01.jpg

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