Department of Applied Psychology, Government College University Faisalabad, Zakid Block 1st floor, Main Campus, Faisalabad, Punjab, Pakistan.
Department of Professional Psychology, Bahria University Lahore Campus, Lahore, Pakistan.
BMC Psychiatry. 2022 Mar 29;22(1):222. doi: 10.1186/s12888-022-03863-w.
Cancer is a common worldwide illness; it evokes psychological distress at different stages, during chemotherapy patient perceives a variety of psychiatric symptoms due to various medication side-effects and psychological distress. Studies have shown a significant impact of cognitive behavior therapy (CBT) in the management of psychiatric symptoms during chemotherapy. This study aims to investigate the effectiveness of CBT for depression, anxiety, stress, death anxiety, satisfaction with life, and self-esteem among cancer patients during chemotherapy (CPdC).
Place and duration of the study: Department of Applied Psychology, Government College University Faisalabad in collaboration with Department of Oncology, Allied Hospital Faisalabad from November 20, 2020 and July 31, 2021. A total of 90 cancer patients were enrolled. 70 out of 90 met the eligibility criteria and 60 participants fulfilled all requirements. Participants were randomly allocated to four different groups. The pre-assessment screening was started along with the first trial of chemotherapy. The CBT-based treatment plan was formulated and one session per week was given to each patient for 3 to 4 months. Participants' age range was 18-65 years (M ± SD = 47.51 ± 12.36. Demographic form, Depression Anxiety and Stress Scale (DASS), Death Anxiety Scale (DAS), Satisfaction with Life Scale (SWLS), and Rosenberg Self-Esteem Scale (RSES) were administered. Descriptive, t-test, and repeated measure ANOVA statistics were used to investigate the findings.
Results indicated significant mean difference on the variable of depression, anxiety and stress across four conditions (i.e. F(2, 56) = 39.55, p < .000, η = .679; F(2,56) = 73.32, p < .000, η = .797; F(2,56) = 119.77, p < .000, η = .865 respectively). On death anxiety significant difference across four conditions was found (F(2,56) = 22.71, p < .000, η = .549) with large effect size. Furthermore, findings indicated significant mean difference on the variable of satisfaction with life and self-esteem across four conditions was found (F(2,56) = 22.05, p < .000, η = .542; F(2,56) = 36.19, p < .000, η = .660) with large effect size.
It is concluded that CBT played a very effective role to reduce depression, anxiety, and stress-related psychiatric symptoms. CBT reduces the level of death anxiety and improving the quality of life and level of self-esteem among CPdC.
The study trial was registered in the Thai Clinical Trial Registry-TCTR ( TCTR20201113002 ).
癌症是一种常见的全球疾病；它在化疗的不同阶段引起心理困扰，患者由于各种药物副作用和心理困扰而感知到各种精神症状。研究表明认知行为疗法（CBT）在化疗期间管理精神症状方面具有显著影响。本研究旨在探讨 CBT 对癌症患者化疗期间（CPdC）的抑郁、焦虑、压力、死亡焦虑、生活满意度和自尊的影响。
研究地点和时间：政府学院应用心理学系与费萨拉巴德联合医院肿瘤系于 2020 年 11 月 20 日至 2021 年 7 月 31 日合作。共纳入 90 名癌症患者。其中 70 名符合入选标准，60 名参与者符合所有要求。参与者被随机分配到四个不同的组。在开始第一次化疗试验的同时进行了初步评估筛选。制定了基于 CBT 的治疗计划，并每周为每位患者提供一次治疗，持续 3 至 4 个月。参与者的年龄范围为 18-65 岁（M ± SD = 47.51 ± 12.36。进行了人口统计学表格、抑郁焦虑和压力量表（DASS）、死亡焦虑量表（DAS）、生活满意度量表（SWLS）和罗森伯格自尊量表（RSES）。使用描述性、t 检验和重复测量方差分析统计来调查研究结果。
结果表明，在四个条件下，抑郁、焦虑和压力的变量存在显著的平均差异（即 F(2,56) = 39.55，p <.000，η =.679；F(2,56) = 73.32，p <.000，η =.797；F(2,56) = 119.77，p <.000，η =.865 分别）。在四个条件下，死亡焦虑存在显著差异（F(2,56) = 22.71，p <.000，η =.549），具有较大的效应量。此外，结果表明，在四个条件下，生活满意度和自尊的变量存在显著的平均差异（F(2,56) = 22.05，p <.000，η =.542；F(2,56) = 36.19，p <.000，η =.660），具有较大的效应量。
结论是 CBT 在减少化疗相关的精神症状方面发挥了非常有效的作用。CBT 降低了死亡焦虑的水平，并提高了 CPdC 的生活质量和自尊水平。
该研究试验在泰国临床试验注册处-TCTR（TCTR20201113002）进行了注册。
