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加纳东部地区普通外科人群中的癌症负担。

Burden of cancer in the general surgical population in the eastern region of Ghana.

机构信息

Department of General Surgery, Penn State College of Medicine, Hershey, Pennsylvania, USA.

Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.

出版信息

BMJ Open. 2022 Mar 29;12(3):e051741. doi: 10.1136/bmjopen-2021-051741.

DOI:10.1136/bmjopen-2021-051741
PMID:35351698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8966531/
Abstract

OBJECTIVE

To estimate the surgical burden of malignant disease in the Eastern Region of Ghana.

DESIGN

Descriptive cross-sectional study.

SETTING

Regional hospital in the eastern region of Ghana.

PARTICIPANTS

Patients treated by the surgery department at Eastern Regional Hospital in Koforidua, Ghana.

INTERVENTIONS

None.

PRIMARY AND SECONDARY OUTCOME MEASURES

Primary outcome was incidence of malignancy and secondary outcome descriptive differences between patients who had a benign indication for surgery compared with those with a malignant indication for surgery.

RESULTS

A total of 1943 inpatient surgical procedures were performed from 2015 to 2017 with 13.4% (261) of all procedures ultimately performed for malignancy. Of all breast procedures performed, 95.2% of procedures resulted in a malignant diagnosis. The remaining subtypes of procedures had rates ranging from <1% to 41.2% of procedures performed for malignant disease. Additionally, this study found over 13% of patients admitted to the surgical service for breast cancer ultimately did not undergo a surgical procedure.

CONCLUSION

This is the first study investigating the burden of malignant disease in the Eastern Region of Ghana. We found a substantial prevalence of malignant disease in the surgical population in this region. This information can be used to aid in future medical resource planning in this region.

摘要

目的

评估加纳东部地区恶性疾病的手术负担。

设计

描述性横断面研究。

地点

加纳东部地区科福里杜亚的地区医院。

参与者

在加纳科福里杜亚的东部地区医院接受外科治疗的患者。

干预措施

无。

主要和次要结果测量

主要结果是恶性肿瘤的发病率,次要结果是良性手术指征患者与恶性手术指征患者之间的描述性差异。

结果

2015 年至 2017 年共进行了 1943 例住院手术,其中 13.4%(261 例)最终因恶性肿瘤而进行手术。所有乳房手术中,95.2%的手术结果为恶性诊断。其余手术类型的恶性疾病手术率从<1%到 41.2%不等。此外,本研究发现,超过 13%的因乳腺癌入院的患者最终未进行手术。

结论

这是第一项调查加纳东部地区恶性疾病负担的研究。我们发现该地区外科患者中恶性疾病的患病率很高。这些信息可用于协助该地区未来的医疗资源规划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7a/8966531/90ebce6b19a0/bmjopen-2021-051741f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7a/8966531/90ebce6b19a0/bmjopen-2021-051741f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7a/8966531/90ebce6b19a0/bmjopen-2021-051741f01.jpg

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本文引用的文献

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JCO Glob Oncol. 2020 Apr;6:610-616. doi: 10.1200/JGO.19.00387.
2
Malignant tumours in urban Ghana: evidence from the city of Kumasi.加纳城市的恶性肿瘤:库马西市的证据。
BMC Cancer. 2019 Mar 25;19(1):267. doi: 10.1186/s12885-019-5480-0.
3
Cancer Control in Low- and Middle-Income Countries: Is It Time to Consider Screening?低收入和中等收入国家的癌症控制:是时候考虑筛查了吗?
J Glob Oncol. 2019 Mar;5:1-8. doi: 10.1200/JGO.18.00200.
4
Fear of Mastectomy Associated with Delayed Breast Cancer Presentation Among Ghanaian Women.加纳女性对乳房切除术的恐惧与乳腺癌就诊延迟相关。
Oncologist. 2018 Dec;23(12):1446-1452. doi: 10.1634/theoncologist.2017-0409. Epub 2018 Jun 29.
5
Delayed presentation and diagnosis of breast cancer in African women: a systematic review.非洲女性乳腺癌的延迟就诊与诊断:一项系统评价
Ann Epidemiol. 2017 Oct;27(10):659-671.e7. doi: 10.1016/j.annepidem.2017.09.007. Epub 2017 Sep 22.
6
Cancer Incidence in Five Continents: Inclusion criteria, highlights from Volume X and the global status of cancer registration.《五大洲癌症发病率》:纳入标准、第十卷要点及全球癌症登记现状。
Int J Cancer. 2015 Nov 1;137(9):2060-71. doi: 10.1002/ijc.29670.
7
Profile of cancer patients' seen at Korle Bu teaching hospital in Ghana (a cancer registry review).加纳科勒布教学医院癌症患者概况(癌症登记回顾)
BMC Res Notes. 2014 Aug 27;7:577. doi: 10.1186/1756-0500-7-577.
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Cancer incidence in Ghana, 2012: evidence from a population-based cancer registry.2012年加纳的癌症发病率:基于人群的癌症登记处的数据
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Establishing effective registration systems in resource-limited settings: cancer registration in Kumasi, Ghana.在资源有限的环境中建立有效的登记系统:加纳库马西的癌症登记
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Ghana's burden of chronic non-communicable diseases: future directions in research, practice and policy.加纳慢性非传染性疾病的负担:研究、实践与政策的未来方向
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