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The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis.

作者信息

Yan Renhong, Xie Enjun, Li Yaning, Li Jin, Zhang Yuanyuan, Chi Ximin, Hu Xueping, Xu Lei, Hou Tingjun, Stockwell Brent R, Min Junxia, Zhou Qiang, Wang Fudi

机构信息

Westlake Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, Institute of Biology, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.

Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.

出版信息

Cell Res. 2022 Jul;32(7):687-690. doi: 10.1038/s41422-022-00642-w. Epub 2022 Mar 29.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a58c/9253326/5857cfc81e45/41422_2022_642_Fig1_HTML.jpg

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