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荷兰 2006-2018 年孕产妇死亡情况的保密性调查。

Confidential enquiry into maternal deaths in the Netherlands, 2006-2018.

机构信息

Department of Obstetrics and Gynecology, Leiden University Medical Center, Leiden, the Netherlands.

Department of Obstetrics and Gynecology, Isala Hospital, Zwolle, the Netherlands.

出版信息

Acta Obstet Gynecol Scand. 2022 Apr;101(4):441-449. doi: 10.1111/aogs.14312.

Abstract

INTRODUCTION

To calculate the maternal mortality ratio (MMR) for 2006-2018 in the Netherlands and compare this with 1993-2005, and to describe women's characteristics, causes of death and improvable factors.

MATERIAL AND METHODS

We performed a nationwide, cohort study of all maternal deaths between January 1, 2006 and December 31, 2018 reported to the Audit Committee Maternal Mortality and Morbidity. Main outcome measures were the national MMR and causes of death.

RESULTS

Overall MMR was 6.2 per 100 000 live births, a decrease from 12.1 in 1993-2005 (risk ratio [RR] 0.5). Women with a non-western ethnic background had an increased MMR compared with Dutch women (MMR 6.5 vs. 5.0, RR 1.3). The MMR was increased among women with a background from Surinam/Dutch Antilles (MMR 14.7, RR 2.9). Half of all women had an uncomplicated medical history (79/161, 49.1%). Of 171 pregnancy-related deaths within 1 year postpartum, 102 (60%) had a direct and 69 (40%) an indirect cause of death. Leading causes within 42 days postpartum were cardiac disease (n = 21, 14.9%), hypertensive disorders (n = 20, 14.2%) and thrombosis (n = 19, 13.5%). Up to 1 year postpartum, the most common cause of death was cardiac disease (n = 32, 18.7%). Improvable care factors were identified in 76 (47.5%) of all deaths.

CONCLUSIONS

Maternal mortality halved in 2006-2018 compared with 1993-2005. Cardiac disease became the main cause. In almost half of all deaths, improvable factors were identified and women with a background from Surinam/Dutch Antilles had a threefold increased risk of death compared with Dutch women without a background of migration.

摘要

简介

计算 2006-2018 年荷兰的孕产妇死亡率(MMR),并与 1993-2005 年进行比较,描述妇女的特征、死亡原因和可改善因素。

材料和方法

我们对 2006 年 1 月 1 日至 2018 年 12 月 31 日期间向审计委员会孕产妇死亡率和发病率报告的所有孕产妇死亡进行了全国性队列研究。主要结局指标是全国孕产妇死亡率和死亡原因。

结果

总体 MMR 为每 100000 例活产 6.2 例,较 1993-2005 年的 12.1 例下降(风险比 [RR]0.5)。与荷兰妇女相比,具有非西方族裔背景的妇女 MMR 升高(MMR 6.5 对 5.0,RR1.3)。来自苏里南/荷属安的列斯的妇女 MMR 升高(MMR 14.7,RR2.9)。一半的妇女有简单的医疗史(79/161,49.1%)。在 1 年内产后的 171 例与妊娠相关的死亡中,有 102 例(60%)有直接死因,69 例(40%)有间接死因。产后 42 天内的主要死因是心脏病(n=21,14.9%)、高血压疾病(n=20,14.2%)和血栓形成(n=19,13.5%)。产后 1 年内,最常见的死因是心脏病(n=32,18.7%)。在所有死亡中,有 76 例(47.5%)确定了可改善的护理因素。

结论

与 1993-2005 年相比,2006-2018 年孕产妇死亡率减半。心脏病成为主要死因。在几乎一半的死亡中,确定了可改善的因素,与没有移民背景的荷兰妇女相比,来自苏里南/荷属安的列斯的妇女死亡风险增加了三倍。

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