Int J Periodontics Restorative Dent. 2022 Mar-Apr;42(2):261-267. doi: 10.11607/prd.4863.
This study aimed to evaluate the bone dimensional changes associated with extraction sockets preserved with calcium phosphosilicate (CPS) morsels and platelet-rich fibrin (PRF) at 6 months posthealing. Thirty fresh extraction sockets were randomly allocated to one of the following groups and grafted using PRF: Control (n = 10), CPS morsels (Test I; n = 10), or CPS+PRF (Test II; n = 10). All sites were sealed with PRF as a socket seal. CBCT scans were taken at 1 week postsurgery and at 6 months posthealing. The intergroup comparison showed a statistically significant difference in mean horizontal bone dimensional changes, and no such significance was observed for vertical bone changes. Bone density measured using Hounsfield units (HU) fell within the range of 350 to 850 HU (D3 bone quality) at 6 months posthealing for all three groups. Within the limitations of this study, socket preservation using CPS morsels with and without PRF demonstrated more favorable conditions for future implant placement.
本研究旨在评估在愈合后 6 个月时，使用磷酸钙硅（CPS）颗粒和富血小板纤维蛋白（PRF）保存拔牙窝相关的骨尺寸变化。将 30 个新鲜拔牙窝随机分配到以下组之一，并使用 PRF 进行移植：对照组（n = 10）、CPS 颗粒（测试 I；n = 10）或 CPS+PRF（测试 II；n = 10）。所有部位均用 PRF 作为窝洞密封剂密封。术后 1 周和愈合后 6 个月时进行 CBCT 扫描。组间比较显示，水平骨尺寸变化的平均差异具有统计学意义，而垂直骨变化则无显著差异。愈合后 6 个月时，三组的骨密度均用 Hounsfield 单位（HU）测量，在 350 至 850 HU（D3 骨质量）范围内。在本研究的限制范围内，使用 CPS 颗粒联合和不联合 PRF 进行窝洞保存为未来植入物的放置提供了更有利的条件。
