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通过具有移植专业知识的大学的指导建立新的肝移植中心的模型。

Model for establishing a new liver transplantation center through mentorship from a university with transplantation expertise.

机构信息

Liver and Digestive Organs Transplantation Division, Gastroenterology Department, Clinical Hospital of São Paulo University - HCFMUSP, São Paulo Faculty of Medicine, Universidade de São Paulo - USP, São Paulo, São Paulo, Brazil.

Gastroenterology Division, Botucatu Faculty of Medicine, Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP, São Paulo, São Paulo, Brazil.

出版信息

PLoS One. 2022 Mar 30;17(3):e0266361. doi: 10.1371/journal.pone.0266361. eCollection 2022.

Abstract

BACKGROUND

Setting up new liver transplant (LT) centers is essential for countries with organ shortages. However, good outcomes require experience, because LT learning depends on a high number of surgeries. This study aims to describe how a new center was set up from a partnership between the new center and an experienced one. The step-by-step preparation process, the time needed and the results of the new center are depicted.

MATERIAL AND METHODS

The mentoring process lasted 40 months, in which half of the 52 patients included on the transplant list received LT. After the mentorship, a 22-month period was also analyzed, in which 46 new patients were added to the waiting list and nine were operated on.

RESULTS

The 30-day survival rates during (92.3%) and after (66.7%) the partnership were similar to the other LT centers in the same region, as well as the rates of longer periods. The waiting time on the LT list, the characteristics of the donors and the ischemia times did not differ during or after the mentorship.

CONCLUSION

The partnership between universities is a suitable way to set up LT centers, achieving good results for the institutions and the patients involved.

摘要

背景

在器官短缺的国家,建立新的肝移植(LT)中心至关重要。然而,良好的结果需要经验,因为 LT 的学习取决于大量的手术。本研究旨在描述一个新中心如何通过新中心和经验丰富的中心之间的合作建立起来。描述了新中心的逐步准备过程、所需时间和结果。

材料和方法

指导过程持续了 40 个月,在这期间,移植名单上的 52 名患者中有一半接受了 LT。指导结束后,还对 22 个月的时间进行了分析,在此期间,有 46 名新患者被列入候补名单,9 名患者接受了手术。

结果

合作期间(92.3%)和之后(66.7%)的 30 天生存率与同一地区其他 LT 中心相似,较长时期的生存率也相似。指导期间和之后,LT 名单上的等待时间、供体的特征和缺血时间没有差异。

结论

大学之间的合作是建立 LT 中心的一种合适方式,可以为相关机构和患者带来良好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c2d/8967004/bef308af1ca6/pone.0266361.g001.jpg

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