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富血小板纤维蛋白作为空间填充材料与脱蛋白牛骨在上颌前磨牙即刻种植中的应用:一项随机临床试验。

Immediate implant placement with platelet rich fibrin as space filling material versus deproteinized bovine bone in maxillary premolars: A randomized clinical trial.

机构信息

Department of Implantology, Faculty of Dentistry, Cairo University, Cairo, Egypt.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, British University of Egypt, Cairo, Egypt.

出版信息

Clin Implant Dent Relat Res. 2022 Jun;24(3):320-328. doi: 10.1111/cid.13075. Epub 2022 Mar 30.

Abstract

BACKGROUND

Several biomaterials have been suggested to augment the jumping gap during immediate implant placement.

PURPOSE

The aim of this study was to compare the effect of xenograft or platelet derived growth factor (PRF) to graft the jumping gap in immediate implant placement in the maxillary premolar region.

MATERIALS AND METHODS

Twenty patients underwent atraumatic extraction followed by immediate placement. The patients were equally divided into two groups. The first group received xenograft as a jumping gap filling material. The second group received PRF to graft the jumping gap. All patients received preoperative, immediate postoperative, and 6 months postoperative cone beam CT scan (CBCT). Implant stability quotient ISQ values were taken for the installed implants immediate postoperative and at 6 months.

RESULTS

Implants receiving PRF as a jumping gap graft material demonstrated a significantly greater amount of crestal bone loss 1.85 ± 0.89 mm as compared to xenograft group 0.77 ± 0.32 mm (t = 3.52, p = 0.005). PRF group showed significantly greater reduction in buccopalatal direction 1.63 mm as compared to xenograft group 0.59 mm (t = 4014, p <0.001). ISQ values were similar immediately postoperative (t = 0.070, p = 0.945) while the ISQ values were significantly lower in PRF group as compared to xenograft graft at the six-month interval (t = 0.248, p = 0.023).

CONCLUSION

The use of xenograft material as a jumping gap filling material resulted in superior results compared to PRF with regards to crestal bone loss, buccolingual socket reduction, and ISQ values.

摘要

背景

已经有几种生物材料被建议用于增加即刻种植时的跳跃间隙。

目的

本研究的目的是比较异种移植物或血小板衍生生长因子(PRF)在即刻种植中填补跳跃间隙的效果。

材料和方法

20 名患者接受了无创伤性拔牙,随后进行了即刻种植。患者被平均分为两组。第一组接受异种移植物作为跳跃间隙填充材料。第二组接受 PRF 来填补跳跃间隙。所有患者在术前、即刻术后和 6 个月后接受锥形束 CT 扫描(CBCT)。对植入的种植体即刻术后和 6 个月时的种植体稳定性指数(ISQ)值进行了测量。

结果

接受 PRF 作为跳跃间隙移植材料的种植体显示出明显更大的牙槽嵴骨吸收量,为 1.85±0.89mm,而异种移植物组为 0.77±0.32mm(t=3.52,p=0.005)。PRF 组在颊腭向的减少量明显更大,为 1.63mm,而异种移植物组为 0.59mm(t=4014,p<0.001)。即刻术后 ISQ 值相似(t=0.070,p=0.945),而在 6 个月间隔时,PRF 组的 ISQ 值明显低于异种移植物组(t=0.248,p=0.023)。

结论

与 PRF 相比,异种移植物材料作为跳跃间隙填充材料在牙槽嵴骨吸收、颊舌向牙槽窝缩小和 ISQ 值方面的结果更好。

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