School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA
Department of Surgery, Division of Plastic Surgery, University of Rochester Medical Center, Rochester, New York, USA.
BMJ Case Rep. 2022 Mar 30;15(3):e249288. doi: 10.1136/bcr-2022-249288.
Merkel cell carcinoma (MCC) is a rare and highly aggressive skin cancer which most commonly occurs on the head and neck. A limited number of cases of MCC of the hand have been reported in the English literature. We describe a case of MCC of the hand in a man in his late 60s. The lesion presented on the dorsum of the left fifth digit, with metastasis to the left axillary lymph nodes. The primary lesion grew rapidly over a span of 3 months. The patient was treated with two courses of neoadjuvant nivolumab, amputation of the digit and left axillary lymph node resection followed by radiotherapy to the left hand and left axilla. He continues to follow-up for radiotherapy treatment 3 months postoperatively.
默克尔细胞癌（Merkel cell carcinoma，MCC）是一种罕见且高度侵袭性的皮肤癌，最常发生于头部和颈部。英文文献中仅报道过少数手部 MCC 的病例。我们描述了一位 60 多岁男性手部 MCC 的病例。病变发生于左手第五指背侧，伴有左侧腋窝淋巴结转移。原发性病变在 3 个月内迅速生长。患者接受了两周期的新辅助纳武利尤单抗治疗，随后进行了截肢和左侧腋窝淋巴结清扫，以及左手和左侧腋窝的放疗。术后 3 个月，他继续接受放疗治疗。
