Suppr超能文献

手部 Merkel 细胞肿瘤的独特表现。

Unique presentation of Merkel cell tumour affecting the hand.

机构信息

School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA

Department of Surgery, Division of Plastic Surgery, University of Rochester Medical Center, Rochester, New York, USA.

出版信息

BMJ Case Rep. 2022 Mar 30;15(3):e249288. doi: 10.1136/bcr-2022-249288.

Abstract

Merkel cell carcinoma (MCC) is a rare and highly aggressive skin cancer which most commonly occurs on the head and neck. A limited number of cases of MCC of the hand have been reported in the English literature. We describe a case of MCC of the hand in a man in his late 60s. The lesion presented on the dorsum of the left fifth digit, with metastasis to the left axillary lymph nodes. The primary lesion grew rapidly over a span of 3 months. The patient was treated with two courses of neoadjuvant nivolumab, amputation of the digit and left axillary lymph node resection followed by radiotherapy to the left hand and left axilla. He continues to follow-up for radiotherapy treatment 3 months postoperatively.

摘要

默克尔细胞癌(Merkel cell carcinoma,MCC)是一种罕见且高度侵袭性的皮肤癌,最常发生于头部和颈部。英文文献中仅报道过少数手部 MCC 的病例。我们描述了一位 60 多岁男性手部 MCC 的病例。病变发生于左手第五指背侧,伴有左侧腋窝淋巴结转移。原发性病变在 3 个月内迅速生长。患者接受了两周期的新辅助纳武利尤单抗治疗,随后进行了截肢和左侧腋窝淋巴结清扫,以及左手和左侧腋窝的放疗。术后 3 个月,他继续接受放疗治疗。

相似文献

1
Unique presentation of Merkel cell tumour affecting the hand.手部 Merkel 细胞肿瘤的独特表现。
BMJ Case Rep. 2022 Mar 30;15(3):e249288. doi: 10.1136/bcr-2022-249288.
7
Merkel cell tumor of the hand: report of two cases.
J Hand Surg Am. 2008 Mar;33(3):404-6. doi: 10.1016/j.jhsa.2007.12.003.
9
Merkel cell carcinoma of the eyelid: management and prognosis.眼睑 Merkel 细胞癌:治疗和预后。
JAMA Ophthalmol. 2014 Feb;132(2):197-204. doi: 10.1001/jamaophthalmol.2013.6077.

本文引用的文献

1
Merkel Cell Carcinoma of the Hand in a Young Patient.一名年轻患者手部的默克尔细胞癌
J Hand Surg Glob Online. 2020 Nov 17;3(1):61-65. doi: 10.1016/j.jhsg.2020.10.004. eCollection 2021 Jan.
2
Merkel cell carcinoma in the hand. Report of two cases.手部默克尔细胞癌。两例报告。
Case Reports Plast Surg Hand Surg. 2022 Jan 21;9(1):41-45. doi: 10.1080/23320885.2021.2025378. eCollection 2022.
3
Immunotherapy for Non-melanoma Skin Cancer.非黑色素瘤皮肤癌的免疫疗法。
Curr Oncol Rep. 2021 Aug 27;23(11):125. doi: 10.1007/s11912-021-01120-z.
6
Updates on Merkel Cell Carcinoma. Merkel 细胞癌研究进展。
Dermatol Clin. 2019 Oct;37(4):489-503. doi: 10.1016/j.det.2019.06.002.
8
Merkel Cell Carcinoma Review.默克尔细胞癌综述。
Hematol Oncol Clin North Am. 2019 Feb;33(1):39-52. doi: 10.1016/j.hoc.2018.08.002.
9
An enlarging subcutaneous nodule on the hand.手部一个不断增大的皮下结节。
JAAD Case Rep. 2018 May 25;4(6):507-508. doi: 10.1016/j.jdcr.2017.09.031. eCollection 2018 Jul.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验