Department of Geriatrics Neurosciences and Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Lazio, Italy.
Department of Geriatrics Neurosciences and Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Lazio, Italy
BMJ Case Rep. 2022 Mar 30;15(3):e248597. doi: 10.1136/bcr-2021-248597.
Primary lymphoma of the peripheral nerve is very rare and occurs most frequently in sciatic nerves. We describe the first patient reported in literature with a primary lymphoma in a pure sensory peripheral nerve of the upper limb. A woman in her 40s, with painful swelling and dysaesthesias in her left forearm in the past 3 months, was presented at our unit. Clinical MRI and ultrasound findings revealed a lesion that showed signs of a peripheral nerve sheath tumour. After complete excision, morpho-pathological evaluation revealed a primary B-cell lymphoma. The patient underwent radiotherapy and at the last follow-up there were no signs of residual pathology. Peripheral neuropathy may be caused by a lymphoma involving the nerve. Hand surgeons have to distinguish primary lymphoma of the peripheral nerves from schwannoma for their different clinical behaviour.
周围神经原发性淋巴瘤非常罕见，最常发生于坐骨神经。我们描述了首例文献报道的发生于上肢单纯感觉周围神经的原发性淋巴瘤。一位 40 多岁的女性，在过去 3 个月中出现左前臂疼痛性肿胀和感觉异常，就诊于我院。临床 MRI 和超声检查结果显示病变提示为外周神经鞘肿瘤。经完整切除后，形态病理学评估显示为原发性 B 细胞淋巴瘤。患者接受了放疗，末次随访时未见残留病变征象。累及神经的淋巴瘤可能导致周围神经病变。手外科医生必须区分不同的临床行为，将外周神经原发性淋巴瘤与神经鞘瘤区分开来。
