Department of Clinical Pharmacy and Pharmacy Management, Nnamdi Azikiwe University, Awka, Anambra, Nigeria
Research Group for Evidence-Based Health Care, Nnamdi Azikiwe University, Awka, Anambra, Nigeria.
BMJ Open. 2022 Mar 30;12(3):e056901. doi: 10.1136/bmjopen-2021-056901.
Breast cancer is the most prevalent cancer and the second leading cause of cancer-related deaths among women in low and middle-income countries (LMICs), including sub-Saharan Africa. Mammography screening is the most effective screening method for the early detection of breast cancers in asymptomatic individuals and the only screening test that decreases the risk of breast cancer mortality. Despite the perceived benefits, it has a low utilisation rate in comparison with breast self-examination and clinical breast examination. Several interventions to increase the uptake of mammography have been assessed as well as systematic reviews on mammography uptake. Nonetheless, none of the published systematic reviews focused on women living in LMICs. The review aims to identify interventions that increase mammography screening uptake among women living in LMICs.
Relevant electronic databases will be systematically searched from 1 January 1990 to 30 June 2021 for published and grey literature, including citation and reference list tracking, on studies focusing on interventions to increase mammography screening uptake carried out in LMICs and written in the English language. The search will incorporate the key terms: mammography, interventions, low- and middle-income countries and their associated synonyms. Randomised controlled trials, observational studies and qualitative and mixed methods studies of interventions (carried out with and without comparison groups) reporting interventions to increase mammography screening uptake in LMICs will be identified, data extracted and assessed for methodological quality by two independent reviewers with disagreements to be resolved by consensus or by a third author. We will use narrative synthesis and/or meta-analysis depending on the characteristics of the data.
Ethical approval is not required as it is a protocol for a systematic review. Findings will be disseminated through peer-reviewed publications and conference presentations.
CRD42021269556.
乳腺癌是中低收入国家（LMICs），包括撒哈拉以南非洲地区，女性中最常见的癌症和癌症相关死亡的第二大原因。乳腺 X 线摄影筛查是无症状人群中早期发现乳腺癌的最有效筛查方法，也是唯一可以降低乳腺癌死亡率的筛查试验。尽管乳腺 X 线摄影筛查被认为具有益处，但与自我乳房检查和临床乳房检查相比，其利用率较低。已经评估了多种增加乳腺 X 线摄影检查率的干预措施，以及关于乳腺 X 线摄影检查率的系统评价。然而，没有一项已发表的系统评价专门针对生活在 LMICs 的女性。本综述旨在确定增加生活在 LMICs 的女性进行乳腺 X 线摄影筛查的干预措施。
将从 1990 年 1 月 1 日至 2021 年 6 月 30 日，系统地搜索相关电子数据库，以获取发表的和灰色文献，包括对在 LMICs 中开展的旨在提高乳腺 X 线摄影筛查率的干预措施的研究的引文和参考文献跟踪，这些研究用英语撰写。检索将包括以下关键词：乳腺 X 线摄影、干预措施、中低收入国家及其相关同义词。将确定并提取随机对照试验、观察性研究和定性及混合方法研究的干预措施的数据，并由两名独立审查员评估方法学质量，对于存在分歧的情况，将通过共识或由第三位作者解决。我们将根据数据的特征使用叙述性综合或荟萃分析。
由于这是系统评价的方案，因此不需要伦理批准。研究结果将通过同行评议的出版物和会议报告进行传播。
PROSPERO 注册号：CRD42021269556。
