人粪相关细小病毒（细小病毒科）在山羊和绵羊中的存在。
Human-stool-associated tusavirus (Parvoviridae) in domestic goats and sheep.
机构信息
Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti út 12., Pécs, 7624, Hungary.
Vitalant Research Institute, San Francisco, CA, USA.
出版信息
Arch Virol. 2022 May;167(5):1307-1310. doi: 10.1007/s00705-022-05424-8. Epub 2022 Mar 31.
In this study, genetic counterparts of the human-stool-associated tusavirus (subfamily Parvovirinae, family Parvoviridae) with >97% and 95-100% amino acid sequence identity in the parvoviral NS1 and VP1 protein were identified in faecal specimens from domestic goats (Capra hircus) and sheep (Ovis aries) in Hungary. Eleven (17.8%) of the 62 faecal specimens from goats and 12 (25.5%) of the 47 from sheep both from less than 12 months old animals were positive for tusavirus DNA by PCR, while none of the specimens collected from cattle and swine were positive. Thus, it cannot be ruled out that tusavirus infection in humans is of zoonotic origin.
在这项研究中，在匈牙利从家养山羊（Capra hircus）和绵羊（Ovis aries）的粪便样本中鉴定出了与人粪便相关的细小病毒（细小病毒科，细小病毒科）的遗传对应物，其在细小病毒 NS1 和 VP1 蛋白中的氨基酸序列同一性>97%和 95-100%。通过 PCR，在来自 12 个月以下动物的 62 份山羊粪便样本中有 11 份（17.8%）和在来自 47 份绵羊粪便样本中有 12 份（25.5%）为细小病毒 DNA 阳性，而从牛和猪采集的样本均为阳性。因此，不能排除人类细小病毒感染是动物源的。
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