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椎间盘阻滞术后疼痛缓解程度与疑似椎间盘源性腰痛患者短期手术失能结局的相关性。

Correlation between the degree of pain relief following discoblock and short-term surgical disability outcome among patients with suspected discogenic low back pain.

机构信息

Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland.

Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.

出版信息

Scand J Pain. 2022 Apr 1;22(3):526-532. doi: 10.1515/sjpain-2021-0160. Print 2022 Jul 26.

Abstract

OBJECTIVES

To evaluate how well the degree of pain relief after discoblock predicts the disability outcome of subsequent fusion or total disc replacement (TDR) surgery, based on short-term Oswestry Disability Index (ODI) scores.

METHODS

We retrospectively analyzed a set of patients who had undergone discoblock and subsequent fusion or TDR surgery of the same lumbar intervertebral disc due to suspected discogenic chronic LBP between 2011 and 2018. We calculated the degree of pain relief following discoblock (ΔNRS) and the changes in both absolute and percentual ODI scores (ΔODI and ΔODI%, respectively) following fusion or TDR surgery. We analyzed the statistical significance of ΔNRS and ΔODI and the correlation (Spearman's rho) between ΔNRS and ΔODI%. The fusion and TDR group were analyzed both in combination and separately.

RESULTS

Fifteen patients were eligible for the current study (fusion n=9, TDR n=6). ΔNRS was statistically significant in all groups, and ΔODI was statistically significant in the combined group and in the fusion group alone. The parameters of both decreased. We found a Spearman's rho of 0.57 (p=0.026) between ΔNRS and ΔODI% for the combined group. The individual Spearman's rho values were 0.85 (p=0.004) for the fusion group and 0.62 (p=0.191) for the TDR group.

CONCLUSIONS

We suggest that discoblock is a useful predictive criterion for disability outcome prior to surgery for discogenic LBP, especially when stabilizing spine surgery is under consideration.

ETHICAL COMMITTEE NUMBER

174/2019 (Oulu University Hospital Ethics Committee).

摘要

目的

基于短期 Oswestry 功能障碍指数(ODI)评分,评估椎间盘内阻滞(discoblock)治疗后疼痛缓解程度对后续融合或全椎间盘置换(TDR)手术的残疾结局的预测效果。

方法

我们回顾性分析了一组因疑似椎间盘源性慢性下腰痛(LBP)于 2011 年至 2018 年接受 discoblock 治疗且随后对同一腰椎间盘行融合或 TDR 手术的患者。我们计算了 discoblock 治疗后的疼痛缓解程度(ΔNRS)以及融合或 TDR 手术后 ODI 评分的绝对和百分比变化(分别为 ΔODI 和 ΔODI%)。我们分析了 ΔNRS 和 ΔODI 的统计学意义以及 ΔNRS 和 ΔODI%之间的相关性(Spearman's rho)。融合和 TDR 组分别进行了分析。

结果

15 例患者符合当前研究标准(融合组 9 例,TDR 组 6 例)。所有组的 ΔNRS 均具有统计学意义,且联合组和融合组的 ΔODI 具有统计学意义。参数均降低。我们发现联合组的 ΔNRS 和 ΔODI%之间的 Spearman's rho 为 0.57(p=0.026)。融合组的个体 Spearman's rho 值为 0.85(p=0.004),TDR 组为 0.62(p=0.191)。

结论

我们建议 discoblock 是椎间盘源性 LBP 患者术前残疾结局的一个有用的预测指标,特别是在考虑脊柱稳定手术时。

伦理委员会编号

174/2019(奥卢大学医院伦理委员会)。

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