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新冠病毒检测呈阳性的非裔美国患者的皮肤表现

Cutaneous Manifestations in COVID-19-Positive African American Patients.

作者信息

Bryan Avery, Samant Hrishikesh, Asarkar Ameya, Nathan Cherie-Ann O, Khandelwal Alok

机构信息

Department of Otolaryngology, Head and Neck Surgery, Ochsner-Louisiana State University Health, Shreveport, LA.

Multi-Organ Transplant Institute, Ochsner Clinic Foundation, New Orleans, LA.

出版信息

Ochsner J. 2022 Spring;22(1):22-25. doi: 10.31486/toj.21.0057.

Abstract

The United States of America is the leading country in confirmed cases of and deaths from severe acute respiratory syndrome coronavirus 2, the virus that causes coronavirus disease 2019 (COVID-19). In April and May 2020, respectively, 0.2% of patients in a Chinese COVID-19-positive cohort and 20.4% of patients in an Italian COVID-19-positive cohort developed cutaneous abnormalities. Cutaneous abnormalities associated with COVID-19 are not well documented or discussed, and investigation of cutaneous manifestations is necessary to determine if they have any clinical value. We conducted a retrospective study of COVID-19-positive patients who were admitted to Ochsner-Louisiana State University-Shreveport and Ochsner-Louisiana State University-Monroe facilities in Louisiana. Cutaneous manifestations were determined from clinical notes, descriptions in medical records, and a billing code for skin rashes. Of 1,086 COVID-19-positive patients investigated, 871 were African American and 130 were Caucasian. Only 10 patents exhibited probable COVID-19-induced cutaneous abnormalities: 6 (0.7%) of the 871 African American patients and 4 (3.1%) of the 130 Caucasian patients. Dermatologic abnormalities included pruritic or erythematous rash and hypopigmentation of the face, upper chest, abdomen, and trunk areas. Our data are consistent with the smaller percentage of patients in the Chinese cohort study vs the larger percentage in the Italian cohort study. Our data provide evidence that cutaneous manifestations of COVID-19, especially in African American patients, are rare, but documentation of more cases is necessary to establish a cause and effect for COVID-19-induced skin manifestations.

摘要

美利坚合众国是严重急性呼吸综合征冠状病毒2(导致2019冠状病毒病即COVID-19的病毒)确诊病例和死亡人数最多的国家。2020年4月和5月,在中国COVID-19阳性队列中的患者有0.2%出现皮肤异常,而在意大利COVID-19阳性队列中的患者有20.4%出现皮肤异常。与COVID-19相关的皮肤异常情况记录和讨论得并不充分,有必要对皮肤表现进行调查,以确定它们是否具有任何临床价值。我们对路易斯安那州奥克施纳-路易斯安那州立大学什里夫波特分校和奥克施纳-路易斯安那州立大学门罗分校收治的COVID-19阳性患者进行了一项回顾性研究。通过临床记录、病历描述和皮疹计费代码来确定皮肤表现。在接受调查的1086例COVID-19阳性患者中,871例为非裔美国人,130例为白种人。只有10例患者表现出可能由COVID-19引起的皮肤异常:871例非裔美国患者中有6例(0.7%),130例白种人患者中有4例(3.1%)。皮肤异常包括瘙痒性或红斑性皮疹以及面部、上胸部及腹部和躯干部位的色素减退。我们的数据与中国队列研究中患者比例较小、而意大利队列研究中患者比例较大的情况一致。我们的数据表明,COVID-19的皮肤表现,尤其是在非裔美国患者中,较为罕见,但需要记录更多病例,以确定COVID-19引起的皮肤表现之间的因果关系。

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