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过去两个世纪(1789 - 1989年)法国毒理学简史。

A brief history of toxicology in France during the last two centuries (1789-1989).

作者信息

Bonnemain B, Ricordel I

机构信息

Société d'histoire de la Pharmacie, France.

出版信息

Toxicol Rep. 2022 Mar 23;9:505-512. doi: 10.1016/j.toxrep.2022.03.005. eCollection 2022.

Abstract

The history of toxicology in France over the last two centuries has been marked by numerous authors who have progressively broadened the fields of investigation: initially concerned with criminal or accidental poisonings, they have also taken an interest in the environment, workers' health, doping and illicit products, the dangers of radioactivity or combat gases, the risks associated with drugs, etc. Often pharmacists, these toxicology experts were specialists in analytical chemistry and developed numerous methods to refine the detection and characterization of potentially toxic products, and to better understand the mechanisms of toxicity produced by these substances.

摘要

在过去两个世纪里,法国毒理学的历史上涌现出众多作者,他们逐渐拓宽了研究领域:最初关注刑事或意外中毒事件,后来也对环境、工人健康、兴奋剂和违禁产品、放射性或战斗气体的危害、与药物相关的风险等产生了兴趣。这些毒理学专家通常是药剂师,他们是分析化学领域的专家,开发了许多方法来完善对潜在有毒产品的检测和鉴定,并更好地理解这些物质产生毒性的机制。

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